Protein Alignment cutlet and rfc-1

DIOPT Version :10

• Sequence 1: NP_787969.1
• Gene: cutlet / 44637
• FlyBaseID: FBgn0015376
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: NP_001256606.1
• Gene: rfc-1 / 179967
• WormBaseID: WBGene00004337
• Length: 839
• Species: Caenorhabditis elegans
• Alignment Length: 1034
• Identity: 219/1034 - (21%)
• Similarity: 356/1034 - (34%)
• Gaps: 338/1034 - (32%)

  Fly    33 DGPST---SKQAAEKQKENRAPVAALRDSTRLGNSTLGSPQLSQITFGASQLGGEEEAEGTSS-- 92
            |.|.|   .|:||...|:...||....|.....|    :|| .:.....|:...:||::.||.
 Worm    16 DMPFTQEKQKKAATPAKKRTKPVVLTDDDEEEEN----APQ-KKTAPKRSRKQEKEESDITSDED 75

  Fly    93 ----GGQVNRRLFGTPKGPPVG--------RGCSTPFQRMPAIQELENTQLTSRSYGLEKENAAA 145
                |....::..|..|..|||        :..|:..:|....:::|.|.:....:.......:|
 Worm    76 ELVRGTDEKKKRKGGKKELPVGQKTLDYMFKPSSSSSKRDDPKKKVEKTLVNPADFFKNSPAPSA 140

  Fly   146 NQLQEVGLKNVNK---------------------RRLERDLFGDIDDLFHESYEDPMVKKARTEE 189
            ::|.:|..|.|.|                     :::..|.|.|.||.| ::: .|:..|.:|.|
 Worm   141 SKLPKVAPKTVEKPKTPAKKPVEISPSTKENTKTKKVSDDEFVDSDDSF-DTF-TPITVKKKTPE 203

  Fly   190 QRDHEAIERILELRRKMRESSKTLRKDDVSRLKALHDFKMRNLSYEIPNWPFLAIQRSDLERIYV 254
            :|                  .:|.:|.::..:|.           |.|.          .:.|.|
 Worm   204 KR------------------KETPKKKELPSVKK-----------EFPK----------KQSIPV 229

  Fly   255 RFHSEDYEQRQLDLISARGEVVGSLLGEAKD--KIWQEAGEIVLSRATAAEDADVTLVNSNANSE 317
            :...|..:::.|.:              .||  |:..|:     |.::....:.|......:...
 Worm   230 KKEKETPQKKALSV--------------KKDPPKVTSES-----SSSSQVSTSSVVFQPKPSGPP 275

  Fly   318 PGRLWVDKYKPRKYIDLL---SDEMTNRSLLYWLKMWDKVVFGKAFHSKREQEA--VTGEGGTAG 377
            |...|||||||::..:|:   .|:.....||.|:|.|.|...|:....|:.:.|  ::.:.||
 Worm   276 PALSWVDKYKPKRMGELVGQNGDKSPINKLLEWIKDWAKHNLGEGAKIKKPKPAPWMSSQDGT-- 338

  Fly   378 GAANQLNSFNKRTGKFESNGGWRQRKSRQALNTNVDALGRPMQKVALLCGPPGLGKTTLAHTIAR 442
                   ||                                  |.|||.|.||:||||.|:...:
 Worm   339 -------SF----------------------------------KAALLSGSPGVGKTTCAYMACQ 362

  Fly   443 HAGYNVREINASDDRSPEAFKLALEN-----------GTQMSSVLNEDKRPNCIVLDEIDG---- 492
            ..|..:.|:||||.||.:..:..:..           |.:..:..:..|..:.:::||:||
 Worm   363 QLGLQLVEMNASDVRSKKHLEAKIGELSGSHQIEQFFGAKKCAPQDNQKVHHILIMDEVDGMSGN 427

  Fly   493 APRQSIDYLVKFISDAVYTKVKAKGAKAEHNVLKRPIICICNDVYDPALRPLRQVAFVVTFPPID 557
            ..|..|..|::.|.::                 |.||||||||...|.:|.|....:.:.||...
 Worm   428 EDRAGISELIQIIKES-----------------KIPIICICNDRQHPKIRTLANYCYDLRFPKPR 475

  Fly   558 AARLAERLVKIAFKEQLKTDFGSLIALAEKSGNDVRSCISSMQFFNAQKHSLTLQDVLNNNLGQK 622
            ...:..|::.|..:|::|.....|..:.|.||:|||..|     :|.|..|..:...:|    ||
 Worm   476 VETIRSRMMTICSQEKMKIGKEELDEIIELSGHDVRQTI-----YNLQMRSKGVGAKIN----QK 531

  Fly   623 DRHQGLFAVWDAIFRIQRPRKTLHTDANKVDEPAQVTMTNTSVTTRVRNVLEVVHSSGDYERLTQ 687
            |.....|:   |..|:...|.||.       |..::..|                   ||..:..
 Worm   532 DMAVDAFS---AARRLLDSRTTLM-------EKQEMFFT-------------------DYGIMPL 567

  Fly   688 GVYENYLQQK----MPDPNFTGVCEALKWFCFTDTVQHQISRQQNYSVYPYLQYGFVAWHLL--- 745
            .|.:|||..|    .|.....|:.:|..:....|.:..||.             |..:|.||
 Worm   568 FVQDNYLNMKNEKHSPIQAIRGIRKAADFISLGDLIDRQIR-------------GGGSWKLLNEQ 619

  Fly   746 -FATLAWPKIA----------FPTRGFEFQQKST--NQRNIFQALCKGVTTSALGVGQG-GTLLL 796
             ..:.|.|.||          ||:   ...:.||  .::.:.|.|   |..:.|.|..| .:...
 Worm   620 SMISAALPAIATGGHLKAMIQFPS---WLGKNSTAGKRKRLLQQL---VQHTHLKVSAGTHSFAT 678

  Fly   797 DTVPLLK-RILSPQLRSVAVQLLSPKEQQDLRHTIEVMVDLGLTFVQVKSQEGHYVFQTEPDLDA 860
            |..|:|: :|..|.|.         .|...:...|..|.:..|               .:.|.:|
 Worm   679 DYAPMLRQKITKPLLE---------HEADGIPDVISTMTEYDL---------------IKDDTEA 719

  Fly   861 LS---AFPGYTGLSLPYFSRQLIAREVDLERIRRAAPKGGAPSAPAAK--KKTSGAAAQLPNHLQ 920
            |:   |:||                ::|                ||:|  .|...:..:..|  :
 Worm   720 LTEIVAWPG----------------KID----------------PASKILSKVKASLTRTLN--K 750

  Fly   921 TLKPKPISASNMHSAPKQQLTK-----DFFGRITHK------STSTNSAEESKTDAIVK 968
            |.:..|.|..::....|:.:..     |..|.:..|      .:.....||..||.::|
 Worm   751 TGRMLPYSMDSVSKGKKRGVNSIGIEMDEEGNLVEKFEDEDGESDNEDNEEKTTDVVIK 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cutlet	NP_787969.1	PRK04195	416..>645	CDD:235250	67/243 (28%)
rfc-1	NP_001256606.1	PTZ00121	<4..>245	CDD:173412	54/288 (19%)
		PRK04195	277..805	CDD:235250	155/702 (22%)
		RFC1	597..750	CDD:462507	43/229 (19%)