Protein Alignment cutlet and rfc1

DIOPT Version :10

• Sequence 1: NP_787969.1
• Gene: cutlet / 44637
• FlyBaseID: FBgn0015376
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: XP_073800067.1
• Gene: rfc1 / 100037336
• ZFINID: ZDB-GENE-070410-99
• Length: 1148
• Species: Danio rerio
• Alignment Length: 1064
• Identity: 232/1064 - (21%)
• Similarity: 388/1064 - (36%)
• Gaps: 291/1064 - (27%)

  Fly     6 DENEEFELQYQDE------LELLEDLPDEFNA-YDGPSTSKQAAE------KQKENRAP-VAALR 56
            ||::|.|.|..|:      |.:|:|.|....| .|..|.||.:::      |.|::.:| .:.::
Zfish   217 DEDKELEKQIHDDEEFARTLAMLDDAPLPKKARVDSISPSKSSSQAIASDIKPKKDLSPKTSPVK 281

  Fly    57 DSTRL-------------GNSTLG------SPQLSQITFGASQLGGEEEAEGTSSGGQVNRRLFG 102
            .|::|             |....|      ||:...|:..:|:.....:....|:|...:|.| .
Zfish   282 TSSKLAQMKRRQEERDEQGKKDKGEKQIKISPKKEPISPTSSERAATPKTASASAGMAKSRNL-S 345

  Fly   103 TPKGPPVGRGCSTPFQRMPAIQELENTQLTS---RSYGLEKENAAANQLQEVGLKNV---NKRRL 161
            |||...|....|.......:..:||..:..|   ||| |.:|...|     :|.|::   .:..|
Zfish   346 TPKSESVASKTSPTKPENTSPDDLEKKRANSSAYRSY-LNREGPRA-----LGSKDIPQGEENCL 404

  Fly   162 ERDLF---GDIDDLFHESYEDPMVKKARTEEQRDHEAIER-----ILELRRKM------RES--S 210
            |..:|   |.::.:               |.......|||     ...:.||.      |:|  |
Zfish   405 EGCVFVLTGVLESM---------------ERDEAKSLIERYGGKVTGNVSRKTTYLVLGRDSGVS 454

  Fly   211 KTLRKDDVSRLKALHDFKMRNLSYEIPNWPFLAIQRSDLERIYVRFHSEDYEQRQLDLISARGEV 275
            || .|.:....|.:::.::.:|....|.      ::|..| |.....::..:.|..|   :||:|
Zfish   455 KT-EKAESFGTKIINEDELLDLIRTKPG------KKSKYE-IAAEAENKSSKTRTPD---SRGKV 508

  Fly   276 VGSLL----------------GEAKDKIWQEAGEIVLSRATAAEDADVTL----------VNSNA 314
            ..|..                |::|.....::|    :|..:..:...:|          |:.:|
Zfish   509 ASSAKKATPQGPSPNKRSSSGGKSKPGSASKSG----ARGASCSEVKKSLSFDQTKTASPVSHSA 569

  Fly   315 NSEPGR--LWVDKYKPRKYIDLL---SDEMTNRSLLYWLKMWDKVVFGKAFHSKREQEAVTGEGG 374
            ....|.  ||||||:||...:|:   .|:.....||.||:.|.|      .||           |
Zfish   570 PENDGSSLLWVDKYRPRSLKNLIGQQGDQSCANKLLRWLQSWHK------HHS-----------G 617

  Fly   375 TAGGAANQLNSFNKRTGKFESNGGWRQRKSRQALNTNVDALGRPMQKVALLCGPPGLGKTTLAHT 439
            .|...|.:...|    |..:...|:                     |.|||.||||:||||.|..
Zfish   618 NAKAPAPKFGKF----GSKDDGSGF---------------------KAALLSGPPGVGKTTTAAL 657

  Fly   440 IARHAGYNVREINASDDRSPEAFKLALENGTQMSSVLN-------EDKRPNCIVLDEIDG----A 493
            :....||:..|:|||..||..:.|..:......:|:.|       .....:.:::||:||    .
Zfish   658 VCEELGYSYVEMNASCTRSKNSLKEVIAESLNNTSIKNFYTGASQTVSSKHVLIMDEVDGMAGNE 722

  Fly   494 PRQSIDYLVKFISDAVYTKVKAKGAKAEHNVLKRPIICICNDVYDPALRPLRQVAFVVTFPPIDA 558
            .|..|..::..|..:                 |.||||:|||.....:|.|....:.:.|.....
Zfish   723 DRGGIQEMIGLIKQS-----------------KIPIICMCNDRNHQKIRSLANYCYDLRFQRPRV 770

  Fly   559 ARLAERLVKIAFKEQLKTDFGSLIALAEKSGNDVRSCISSMQFFNAQKHSLTL-QDVLNNNLGQK 622
            .::...::.|||||.||....:|..:...|..|:|..:.::..::|:...:|. |...:.|..:|
Zfish   771 EQIKGAMMSIAFKEGLKIPPPALNEVILASNQDIRQVLHNLSMWSAKDKVMTYDQAKADANNAKK 835

  Fly   623 DRHQGLFAVWDAIFRIQRPRKTLHTDANKVDEPAQVTMTNTSVTTRVRNVLEVVHSSGDYERLTQ 687
            |...|.|.|...:|.:.             :|.|.:::.:.|..        ..|   ||.....
Zfish   836 DMKLGPFDVCRKVFALG-------------EETAHMSLIDKSDL--------FFH---DYSLAPL 876

  Fly   688 GVYENYLQQKMPDPNFTG---------VCEALKWFCFTDTVQHQISRQQNYSVYP---------- 733
            .|.||||..:   |...|         :.:.....|..|.|..||..:|.:|:.|
Zfish   877 FVQENYLHVR---PAAAGGNLKSHLVLLSKTADSICDGDLVDRQIRSKQTWSLLPTQAIYASVLP 938

  Fly   734 -YLQYGFVAWHLLFATLAWPKIAFPTRGFEFQQKSTNQRNIFQALCKGVTTSALGVGQGGTLLLD 797
             .|..|:::        .:|.  ||:...:|.....:.| |.|.|...::...|...:  .:.||
Zfish   939 GELMRGYMS--------QFPN--FPSWLGKFSSSGKHSR-IIQELASHMSLKTLSSKE--AVNLD 990

  Fly   798 TVPLLKRILSPQLRSVAVQLLSPKEQQDLRHTIEVMVDLGL------TFVQVKSQEGHYVFQTEP 856
            .:        |.|||..::.|.....:....::::|.|..:      ..:::.:.:|    |.:|
Zfish   991 YL--------PYLRSAVLKPLQSLGSEGANQSVKLMDDYDIIKEDVDNMMEISTWDG----QPDP 1043

  Fly   857 ----DLDALSAFP-GYTGLS-LPYFSRQLIAR------------EVDLE-RIRRAAPKGGAPSAP 902
                |....:||. .|...| |..:|.|::.:            |:|.| :::......|..:..
Zfish  1044 YSKLDSKVKAAFTRAYNKESHLTPYSLQVVKKSRKGAVDPELLGELDNESQVQEEEEDDGLGADA 1108

  Fly   903 AAKKKTSGAAAQLPNHLQTLKPKP 926
            ..|:|.|..|.:........|.||
Zfish  1109 MIKQKKSKPAKETKPAKDVKKEKP 1132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cutlet	NP_787969.1	PRK04195	416..>645	CDD:235250	63/240 (26%)
rfc1	XP_073800067.1	None