Protein Alignment Cyp4e1 and DIT2

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 456
• Identity: 102/456 - (22%)
• Similarity: 183/456 - (40%)
• Gaps: 89/456 - (19%)

  Fly    65 EYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSD-----VYDLTHPWLGLGLLTSTGSKW 124
            :||.  .:::.|...||:|:..:|:..|...:...:||.     .|.....:.|..::::.|:.|
Yeast    65 KYGA--VKFFFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVISAYGAVW 127

  Fly   125 HKHRKMITPAFHFNILQDFHEVMNENSTKFIDQL--KKVADGGNIFDFQEEAHYLTLDVICDTAM 187
            ..:|..:|     |.||.|.:.....:.|.:..|  .::.:|.........:..:.||.|...|:
Yeast   128 RNYRNAVT-----NGLQHFDDAPIFKNAKILCTLIKNRLLEGQTSIPMGPLSQRMALDNISQVAL 187

  Fly   188 GVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIA 252
            |....|:.:..:    ||.:....||.:.|.|:..........| .|...|..|.:..| .|::.
Yeast   188 GFDFGALTHEKN----AFHEHLIRIKKQIFHPFFLTFPFLDVLP-IPSRKKAFKDVVSF-RELLV 246

  Fly   253 KRIEVRKSGLEVGIKADE------FSRKKMAFLDTLLSSK---VDGRPLTSQELYEEVSTFMFEG 308
            ||::            ||      |.:...|..|.:.:..   :|.:.||     :.:...:..|
Yeast   247 KRVQ------------DELVNNYKFEQTTFAASDLIRAHNNEIIDYKQLT-----DNIVIILVAG 294

  Fly   309 HDTTTSGVGFAVYLLSRHPDE-QEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLY 372
            |:........::|||:::.:| ||||..|...:....||         :.:..|:.|:.|..|:|
Yeast   295 HENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDPKGL---------ADLPLLNAFLFEVVRMY 350

  Fly   373 PSV-PFIGRFTEKDYVIDGDIV-PKGTTLNLGLLMLGYNDRVFKDPH----------KFQPERFD 425
            |.: ..|.|.|.|...:..:|| |||       :.:|||:  |...|          .|:|||:.
Yeast   351 PPLSTIINRCTTKTCKLGAEIVIPKG-------VYVGYNN--FGTSHDPKTWGTTADDFKPERWG 406

  Fly   426 ----------REKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNF--EVLPALDELVSKD 478
                      |..........|..|.|.|:|:|.||.|::..::::::.|  .:.|..:|.::..
Yeast   407 SDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPA 471

  Fly   479 G 479
            |
Yeast   472 G 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	100/453 (22%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	102/456 (22%)