DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e1 and CYP96A13

DIOPT Version :9

Sequence 1:	NP_524771.1	Gene:	Cyp4e1 / 44632	FlyBaseID:	FBgn0015034	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_195910.1	Gene:	CYP96A13 / 831752	AraportID:	AT5G02900	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	504	Identity:	122/504 - (24%)
Similarity:	211/504 - (41%)	Gaps:	106/504 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLP-LVGNAHQMGNTPTEILNR------FFGWWH 64
            |.:|:..|::.:|.||         .:....||| |:...|::.:...|:|..      |.|.|.
plant     9 ASIAIFCFIILHFFLG---------NWPVLGMLPGLLLEFHRIYDFSVEVLENSDLTFPFKGPWF 64

  Fly    65 EYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQ-TLISKSDVYDLTHPWLGLGLLTSTGSKWHKHR 128
            . |.|          .:...:|..:..|:||. :..:|...:.......|.|:||:..|:..|:.
plant    65 T-GMD----------MLFTVDPTNIHHIMSSNFSNYTKGPDFKQVFDVFGDGILTTDDSELWKNL 118

  Fly   129 KMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSINA 193
            |..      :::...|:...:|              |.:.|.|:.......|....|..|    :
plant   119 KKA------SLVMLNHQGFQKN--------------GTVVDLQDVFKRFMFDTTLVTVTG----S 159

  Fly   194 MENRSSSV-------VQAFKDITYTIKMRAFSP---WKRNKYLFHFAPEYPEYSKTLKTL-QDFT 247
            .:.||.|:       .:|...:...|..|...|   ||..|.: .|..| .::||...|| |...
plant   160 ADPRSLSIEMPEVEFAKALDHVGEGIMHRHVRPRLLWKLQKCV-GFGQE-KKFSKADATLNQACA 222

  Fly   248 NEIIAKRIEVRKSGLEVGIKADEFSRKKMAF---LDT----LLSSKVDGRPLTSQELYEEVSTFM 305
            ..|:.||.|.|..|.:......| |...:.:   :||    ||:      |...:.|.:.:..|:
plant   223 KYILEKREETRSQGFDYHSNGSE-SEDILTYHIKIDTTKYELLN------PSDDKFLRDTILAFV 280

  Fly   306 FEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRD----ATFQEISTMKHLDLFIK 366
            ..|.|||.|.:.:..:||..:|....|:..|    :..|..|::    ...:.::.:.:|...:.
plant   281 LAGRDTTASALTWFFWLLLENPQVVTKIRQE----INTSNGGQEKPSCEPMEYLNNLVYLHGALY 341

  Fly   367 EAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLN------LGLLMLGYNDRVF-KDPHKFQPERF 424
            ||.||||.|||     |:...|..|::|.|..::      :.:..||....|: :|..:|:|||:
plant   342 EAMRLYPPVPF-----ERMSPIKPDVLPSGHKVDSSMKILIFIYALGRMRAVWGEDASEFKPERW 401

  Fly   425 ------DREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEV 467
                  .|.:|. |:::.|:||||:|||::.|:..:|.||.:|::|:::
plant   402 LSETTSLRHEPS-FKFLAFNAGPRSCIGKQLAMTLMKIVVVEILQNYDI 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	116/477 (24%)
CYP96A13	NP_195910.1	p450	1..479	CDD:299894	122/504 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H111093
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010