DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e1 and CPD

DIOPT Version :9

Sequence 1:	NP_524771.1	Gene:	Cyp4e1 / 44632	FlyBaseID:	FBgn0015034	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_196188.1	Gene:	CPD / 830453	AraportID:	AT5G05690	Length:	472	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	125/542 - (23%)
Similarity:	211/542 - (38%)	Gaps:	129/542 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AFLALPLFLVTYFELGLLRRKRMLNKFQGPSM--LPLVGNAHQM-GNTPTEILNRF-------FG 61
            |||.|...:...|.| ||||.|.......|..  |||:|...|: |...||....|       :|
plant     5 AFLLLLSSIAAGFLL-LLRRTRYRRMGLPPGSLGLPLIGETFQLIGAYKTENPEPFIDERVARYG 68

  Fly    62 ---WWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHP-----WLGL-GLL 117
               ..|.:|:          ..|...:|:...|:|.::     ..:::.::|     .||. .||
plant    69 SVFMTHLFGE----------PTIFSADPETNRFVLQNE-----GKLFECSYPASICNLLGKHSLL 118

  Fly   118 TSTGSKWHKHRKMITPAF-HFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDV 181
            ...|| .||....:|.:| :.:|::|                                 :|.||:
plant   119 LMKGS-LHKRMHSLTMSFANSSIIKD---------------------------------HLMLDI 149

  Fly   182 ICDTAMGVSINAMENRSSSVVQAFKDITY--TIK-MRAFSP--WK---RNKYLF----HFAPEYP 234
              |..:..::::..:|...:.:| |.||:  |:| :.:|.|  |.   |.:||.    .|:...|
plant   150 --DRLVRFNLDSWSSRVLLMEEA-KKITFELTVKQLMSFDPGEWSESLRKEYLLVIEGFFSLPLP 211

  Fly   235 EYSKTL-KTLQ------DFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSSKVDGRPL 292
            .:|.|. |.:|      :....::.||.|..:.|.|          :|...|..||::. ||  .
plant   212 LFSTTYRKAIQARRKVAEALTVVVMKRREEEEEGAE----------RKKDMLAALLAAD-DG--F 263

  Fly   293 TSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHP-------DEQEKLFNEQCDVMGASGLGRDA 350
            :.:|:.:.:...:..|::||::.:..||..|:..|       :|.||:...:.|       ....
plant   264 SDEEIVDFLVALLVAGYETTSTIMTLAVKFLTETPLALAQLKEEHEKIRAMKSD-------SYSL 321

  Fly   351 TFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKD 415
            .:.:..:|......:.|..|:...:..:.|....|..|.|..:|||..:......:..:...|||
plant   322 EWSDYKSMPFTQCVVNETLRVANIIGGVFRRAMTDVEIKGYKIPKGWKVFSSFRAVHLDPNHFKD 386

  Fly   416 PHKFQPERFDREK--PGPFE-YVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPA-LDELVS 476
            ...|.|.|:....  .||.. :.||..|||.|.|.:.|.:.:...:.:::..|..:|| .|:||
plant   387 ARTFNPWRWQSNSVTTGPSNVFTPFGGGPRLCPGYELARVALSVFLHRLVTGFSWVPAEQDKLV- 450

  Fly   477 KDGYISTTLGLQ--PAEKKSRD 496
               :..||...:  |...|.||
plant   451 ---FFPTTRTQKRYPIFVKRRD 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	103/483 (21%)
CPD	NP_196188.1	p450	1..472	CDD:386267	125/542 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010