DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e1 and CYP72A8

DIOPT Version :9

Sequence 1:	NP_524771.1	Gene:	Cyp4e1 / 44632	FlyBaseID:	FBgn0015034	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_188080.1	Gene:	CYP72A8 / 820690	AraportID:	AT3G14620	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	482	Identity:	132/482 - (27%)
Similarity:	220/482 - (45%)	Gaps:	77/482 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KFQGPSMLP---LVGN----AHQMGNTPTEILNRFFGWWH-----------EYGKDNFRYWIGYY 78
            |.||.|..|   |||:    |..:....:..:|....:.|           ::||.:: .|:|..
plant    44 KRQGLSGTPFTFLVGDIKREASMVEQEKSRPINLTDDYTHRVMPLIQQTVKDHGKTSY-MWMGPI 107

  Fly    79 SNIMVTNPKYMEFILSSQTLISKSDVYDL----THPWLGL---GLLTSTGSKWHKHRKMITPAFH 136
            ::::||.|::::.:|:.        |||.    .||.:.|   |:....|.||.||||:|.|:||
plant   108 ASVIVTKPEHIKDVLNR--------VYDFPKPPVHPIVELFATGVALYEGEKWSKHRKIINPSFH 164

  Fly   137 FNILQDFHEVMNENSTKFIDQLKK-VADGG--NIFDFQEEAHYLTLDVICDTAMGVS-------I 191
            ...|:.......|:.::.|.:.:| |.:.|  |..|.......||.|||..||.|.|       .
plant   165 LEKLKIMIPAFYESCSEMISKWEKLVTEQGSSNEIDVWPYLGDLTSDVISRTAFGSSYEEGKRIF 229

  Fly   192 NAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIE 256
            ...|.:...|::|. ::.:...|| |.|.|.|..:       .:.:|.:|:.   ..|||.|
plant   230 ELQEEQGRRVLKAL-ELAFIPGMR-FLPTKNNLRM-------RQINKEVKSR---LREIIMK--- 279

  Fly   257 VRKSGLEVGIKADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVY 321
             |:.|::.|      ...|...|..||.|......::.:::.||...|.|.|.:||...:.:.:.
plant   280 -RQRGMDTG------EAPKNDLLGILLESNSGDHGMSIEDVVEECRLFHFAGQETTAVLLVWTMI 337

  Fly   322 LLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDY 386
            :||.|...|::...|...|:|.:   ....|..:|.:|.:.:.:.|..||||....:||..||:.
plant   338 MLSHHQKWQDQAREEILKVIGKN---NKPNFDALSRLKTMSMILNEVLRLYPPGILLGRTVEKET 399

  Fly   387 VIDGDI-VPKGTTLNLGLLMLGYNDRVF-KDPHKFQPERF----DREKPGPFEYVPFSAGPRNCI 445
            .:..|: :|.|..:.:.:||:..:..:: :|.|:|.||||    .:.......::||..|||.|.
plant   400 KLGEDMTLPGGAQVVIPVLMVHRDPELWGEDVHEFNPERFADGISKATKNQVSFLPFGWGPRFCP 464

  Fly   446 GQKFALLEIKTVVSKIIR--NFEVLPA 470
            ||.|||:|.|..:..|::  :||:.|:
plant   465 GQNFALMEAKMALVLILQRFSFELSPS 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	130/477 (27%)
CYP72A8	NP_188080.1	p450	26..515	CDD:299894	132/482 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860