Protein Alignment Cyp4e1 and cyp4v2.2

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001072667.1
• Gene: cyp4v2.2 / 780124
• XenbaseID: XB-GENE-977085
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 540
• Identity: 189/540 - (35%)
• Similarity: 285/540 - (52%)
• Gaps: 50/540 - (9%)

  Fly     5 LCAFLALPLFLVTYFELGLL-------RRKRMLNKFQGPS-MLPLVGNAHQMGNTPTEILNRFFG 61
            |..::|..:.|:|...|.:|       |::|:|....||. ..||:|:|..:.|...:...:...
 Frog     9 LLVWVAAAVVLLTLLALSILPALQDYVRKRRILKPIPGPGPNYPLIGDALFLKNNGGDFFLQICE 73

  Fly    62 WWHEYG-KDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWH 125
            :...|. :...:.|||....|:|.:...:|.:|||...:.|:.:|...|||||.|||||||.||.
 Frog    74 YTESYRLQPLLKVWIGTIPFIVVYHADTVEPVLSSSKHMDKAFLYKFLHPWLGKGLLTSTGEKWR 138

  Fly   126 KHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVS 190
            ..||||||.|||.||.:|.|||||.|...:::|:...||.: ||...:.....||:|.:||||..
 Frog   139 SRRKMITPTFHFAILSEFLEVMNEQSKILVEKLQTHVDGES-FDCFMDVTLCALDIISETAMGRK 202

  Fly   191 INAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRI 255
            |.|..||.|..|||...::..|:.|...||....:|:....:..|:.|.||.|..||::.|.:|.
 Frog   203 IQAQSNRDSEYVQAIYKMSDIIQRRQKMPWLWLDFLYAHLRDGKEHDKNLKILHSFTDKAILERA 267

  Fly   256 -EVRKSGLEVGIKAD-----EFSRKKMAFLDTLLSSKVD-GRPLTSQELYEEVSTFMFEGHDTTT 313
             |::|.|.:.....|     :..:|:.||||.||.:..| |..::..::.|||.||||||||||.
 Frog   268 EELKKMGEQKKEHCDSDPESDKPKKRSAFLDMLLMATDDAGNKMSYMDIREEVDTFMFEGHDTTA 332

  Fly   314 SGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFI 378
            :.:.::::||..||:.|.::..|..:|.|.|  .|..|..::..:::|:..|||:.|:|||||..
 Frog   333 AALNWSLFLLGSHPEAQRQVHKELDEVFGKS--DRPVTMDDLKKLRYLEAVIKESLRIYPSVPLF 395

  Fly   379 GRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKP---GPFEYVPFSAG 440
            ||...:|..|.|..||||..:.:....|..:...|.:|.:|:||||..|..   .|:.|:|||||
 Frog   396 GRTVTEDCSIRGFHVPKGVNVVIIPYALHRDPEYFPEPEEFRPERFFPENASGRNPYAYIPFSAG 460

  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDPI 505
            .||||||:|||:|.|.|:|.|:||:.|                            :|...:.:..
 Frog   461 LRNCIGQRFALMEEKVVLSSILRNYWV----------------------------EASQKREELC 497

  Fly   506 LSASMTLKSENGLHLRMKQR 525
            |...:.|:.::|:.:::|.|
 Frog   498 LLGELILRPQDGMWIKLKNR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	174/446 (39%)
cyp4v2.2	NP_001072667.1	p450	45..509	CDD:365848	177/494 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010