Protein Alignment Cyp4e1 and Cyp4f18

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_077764.2
• Gene: Cyp4f18 / 72054
• MGIID: 1919304
• Length: 524
• Species: Mus musculus
• Alignment Length: 560
• Identity: 160/560 - (28%)
• Similarity: 271/560 - (48%)
• Gaps: 99/560 - (17%)

  Fly     2 WIVL------C--AFLALPLFLVTYFELGLLRRKRMLNKF-QGPSMLPLVGN-----AHQMGNTP 52
            |::|      |  |::..|::       |:......|..| |.|....::|:     :.:.|...
Mouse    19 WLLLLLAGASCLLAYILTPIY-------GVFENSLRLRCFPQPPKRNWILGHLGLIQSSEEGLLY 76

  Fly    53 TEILNRFFGWWHEYGKDNFRYWIG-YYSNIMVTNPKYMEFILSSQTLISKSDV--YDLTHPWLGL 114
            .:.|.|.|       :|...:|:| .:..|.:.:|.:::.::.:..|::..|.  |....||||.
Mouse    77 IQSLVRTF-------RDACCWWVGPLHPVIRIFHPAFIKPVVLAPALVAPKDTVFYRFLKPWLGD 134

  Fly   115 GLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIF-DFQEEAHYLT 178
            |||.|||.||.:||:|:|||||||||:.:.:|.|:::.....:.:::|..|:.: :..|....:|
Mouse   135 GLLMSTGDKWSRHRRMLTPAFHFNILKPYVKVFNDSTNIMHAKWQRLASKGSAYLNMFEHISLMT 199

  Fly   179 LDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEY------PEYS 237
            ||.:.........|..| :.|..:.|..:::..:..|      ..:.|.|....|      ..:.
Mouse   200 LDSLQKCVFSFDSNCQE-KPSEYITAILELSTLVARR------HQRLLLHVDLFYYLTHDGMRFR 257

  Fly   238 KTLKTLQDFTNEIIAKRIEVRKSGLEVG----IKADEFSRKKMAFLDTLLSSKVD-GRPLTSQEL 297
            |..:.:.|||:.:|.:|   |::.|:.|    :|| :...|.:.|:|.||.||.: |:.|:.:::
Mouse   258 KACRLVHDFTDAVIRER---RRTLLDQGGVDVLKA-KAKAKTLDFIDVLLLSKDEHGKALSDEDI 318

  Fly   298 YEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEI-----ST 357
            ..|..||||.|||||.||:.:.:|.|:|||:.||:...|..:::      ||...:||     :.
Mouse   319 RAEADTFMFGGHDTTASGLSWILYNLARHPEYQERCRQEVRELL------RDREPEEIEWDDLAQ 377

  Fly   358 MKHLDLFIKEAQRLYPSVPFIGRFTEKDYVI-DGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQP 421
            :..|.:.|||:.||:|.|..|.|...:|.|: ||.::|||....:.:....:|..|:.||..:.|
Mouse   378 LPFLTMCIKESLRLHPPVTAISRCCTQDIVLPDGRVIPKGVISRISIFGTHHNPAVWPDPEVYDP 442

  Fly   422 ERFDREK---PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYIST 483
            .|||.:.   ..|..::||||||||||||.||:.|:|..::..:..|.|||  |:
Mouse   443 FRFDADNVKGRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRVLP--DD---------- 495

  Fly   484 TLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMK 523
                              .:|.....:.|::|.||.|:::
Mouse   496 ------------------KEPRRKPELILRAEGGLWLKVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	144/475 (30%)
Cyp4f18	NP_077764.2	CYP4F	74..515	CDD:410772	147/494 (30%)