Protein Alignment Cyp4e1 and cyp46a1.3

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_073789299.1
• Gene: cyp46a1.3 / 692332
• ZFINID: ZDB-GENE-060519-40
• Length: 499
• Species: Danio rerio
• Alignment Length: 555
• Identity: 139/555 - (25%)
• Similarity: 242/555 - (43%)
• Gaps: 93/555 - (16%)

  Fly     2 WIVLCAFLALPLFLVTYFELGLLRRKRML--NKFQGPSMLPLVGNAHQMGNTPTEILNR------ 58
            |::...|..|....|.:....|...:..|  :...||..     :...:|:.||  :||
Zfish     5 WLLYMLFYLLSAVFVVFLAYCLYIHQVHLKYDHIPGPPR-----DNFLLGHIPT--INRVTKSER 62

  Fly    59 -----FFGWWHEYGK----DNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYD-----LTH 109
                 ...|..:||.    ::|.|.|     |.|..|:..:.|:.|...:....:|.     ...
Zfish    63 HMNDLLLIWAEKYGPVYRLNSFHYVI-----INVHCPEATKTIMMSPKYLKDPFIYKRLFGLFGK 122

  Fly   110 PWLGLGLLTSTGSK-WHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEE 173
            .:||.||:|:|... |::.|:::.|||..:.|:......||.|.:.:|:|:::|.........:.
Zfish   123 RFLGYGLVTATDHDIWYRQRRIMDPAFSSSYLRGLISTFNEMSERLMDKLEEMAINKTPAVMHDL 187

  Fly   174 AHYLTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSK 238
            .:.:|||:||..|.||.:|..:...:...||.:.....:.:....|         |...:|   |
Zfish   188 VNCVTLDIICKVAFGVDLNLFKQTDNPFQQAIEQCLQGMVLDLRDP---------FCKFFP---K 240

  Fly   239 TLKTLQDFTNEIIAKR------IEVRKSGLEVG--IKADEFSRKKMAFLDTLLSSKVDGRPLTSQ 295
            ..|.:|:.....:..|      |:.||:.:|:|  :..|..::    .|.|....||:... ..:
Zfish   241 NWKAIQETKGATVLLRKTGEQWIQNRKTAVEIGEDVPNDILTQ----ILKTAKEEKVNNTK-DHE 300

  Fly   296 ELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKH 360
            ::.:...||...|.:||.:.:.||:..|.|||:..::...|..:|:|..   ||.:::::....:
Zfish   301 QMLDNFVTFFIAGQETTANQLSFAIMELGRHPEIYKRAKAEVDEVLGTK---RDISYEDLGKFTY 362

  Fly   361 LDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFD 425
            |...:||..||||:.|...|:..:|.||:|..:|.|.::.....:....::.||||.||.||||:
Zfish   363 LSQVLKETLRLYPTAPGTNRWLHEDMVINGIKIPGGISVIFSSYVAQRLEKHFKDPLKFDPERFN 427

  Fly   426 REKPGPFE-YVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQP 489
            ...|.|:. |.|||.|||:|:||.|:.:|.|.|::|:::.||.     .||....:....:|
Zfish   428 VNAPKPYYCYYPFSLGPRSCLGQVFSQMEAKVVLAKLLQRFEF-----SLVPGQSFEIKDIG--- 484

  Fly   490 AEKKSRDAHNHKYDPILSASMTLKSENGLHLRMKQ 524
                                 ||:.::|:...:||
Zfish   485 ---------------------TLRPKSGVICNIKQ 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	121/470 (26%)
cyp46a1.3	XP_073789299.1	None