Protein Alignment Cyp4e1 and Cyp4f40

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_006524820.1
• Gene: Cyp4f40 / 631304
• MGIID: 3645508
• Length: 551
• Species: Mus musculus
• Alignment Length: 568
• Identity: 167/568 - (29%)
• Similarity: 266/568 - (46%)
• Gaps: 104/568 - (18%)

  Fly     2 WIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWWH-- 64
            |:.|....|.|..|  :|.:|:   ...|.:|. ..:..|.....::...|......:| |.|
Mouse    35 WLGLGPMSASPWLL--FFLVGI---SWFLARFL-TQLYTLYAKCQRLCGFPQPPKKNWF-WGHLG 92

  Fly    65 -----EYG-----------KDNFRYWIG-YYSNIMVTNPKYMEFILSSQTLIS-KSDV-YDLTHP 110
                 |.|           ...|..|:| ....|.:.:|..:..:||:...:: |.|: |....|
Mouse    93 MSPPTEEGMKQVTELVTTYPQGFMTWLGPIVPLITLCHPDIIRSVLSASAAVAPKDDIFYSFLKP 157

  Fly   111 WLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGG----NIFDFQ 171
            |||.|||.|.|.||::||:|:|||||||||:.:.::.|:::.....:..::|.||    |:|
Mouse   158 WLGDGLLVSAGDKWNRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWLRLASGGSTRLNMF--- 219

  Fly   172 EEAHYLTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNK-------YLFHF 229
            |....:|||.:.......:.|..|..|..:....:..|..:        |||:       .|:..
Mouse   220 ENISLMTLDTLQKCVFSFNSNCQEKPSQYIAAILELSTLAV--------KRNEQLLMHVDLLYRL 276

  Fly   230 APEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVG----IKADEFSRKKMAFLDTLLSSK-VDG 289
            .|:...:.|..:.:.|||:.:|.:|   |::.|:.|    |||...| |.:.|:|.||.:| .||
Mouse   277 TPDGMRFYKACRLVHDFTDAVIQER---RRTLLKHGGDDIIKAKAKS-KTLDFIDVLLLTKDEDG 337

  Fly   290 RPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQE 354
            :.|:.:::..|..||||.|||||.||:.:.:|.|:|||:.||:...|..:::      ||...:|
Mouse   338 KELSDEDIRAEADTFMFRGHDTTASGLSWILYNLARHPEHQERCRQEVQELL------RDRDPKE 396

  Fly   355 I-----STMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVI-DGDIVPKGTTLNLGLLMLGYNDRVF 413
            |     :.:..|.:.|||:.||:|.|..:.|...:|..: ||.|:|||....:.:....:|..|:
Mouse   397 IEWDDLAQLPFLTMCIKESLRLHPPVTMVSRCCTQDISLPDGRIIPKGVICIINIFGTHHNPTVW 461

  Fly   414 KDPHKFQPERFDREK---PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELV 475
            :||..:.|.|||.|.   ..|..::||||||||||||.||:.|:|..::..:..|.:||  |:
Mouse   462 RDPEVYDPFRFDPENIQARSPLSFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRILP--DD-- 522

  Fly   476 SKDGYISTTLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMK 523
                                      .:|.....:.|::|.||.||::
Mouse   523 --------------------------KEPRRKPELILRAEGGLWLRVE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	149/479 (31%)
Cyp4f40	XP_006524820.1	CYP4F	101..542	CDD:410772	149/491 (30%)