Protein Alignment Cyp4e1 and cyp19a1b

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_021326198.1
• Gene: cyp19a1b / 60640
• ZFINID: ZDB-GENE-001103-4
• Length: 513
• Species: Danio rerio
• Alignment Length: 498
• Identity: 123/498 - (24%)
• Similarity: 199/498 - (39%)
• Gaps: 103/498 - (20%)

  Fly    55 ILNRFF--------------GWWHEYGK----DNFRYWIGYYSNIMVTNPKYMEF---------- 91
            :|:|.|              |||...|.    ..| .|:|..:.....|.||...
Zfish    31 LLHRIFGVKNWRNQSALPGPGWWLGLGPVLSYSRF-LWMGIGTACNYYNEKYGSIARVWINGEET 94

  Fly    92 -ILSSQTLISKSDVYDL--THPWLG----------LG------LLTSTGSKWHKHRKMITPAFHF 137
             |||.|.   .|.||.:  ::.:.|          :|      :..|..:||.|.|...|.|...
Zfish    95 VILSKQV---SSAVYHVLKSNNYTGRFASAKGLQCIGMFEQGIIFNSNIAKWKKVRTYFTKALTG 156

  Fly   138 NILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSINAMENRSSSVV 202
            ..||...||....:.:.:|.|::..|.....|.......:.:||.....:.:.:|..|
Zfish   157 PGLQKSVEVCVSATNRQLDVLQEFTDASGHVDVLNLLRCIVVDVSNRLFLRIPLNEKE------- 214

  Fly   203 QAFKDITYTIKM-RAFSPWK----RNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGL 262
                   ..||: |.||.|:    :....|.....|.:|....|.|||    .:.|.:|.::..:
Zfish   215 -------LLIKIHRYFSTWQTVLIQPDIFFKLDFVYRKYHLAAKELQD----EMGKLVEQKRQAI 268

  Fly   263 EVGIKADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHP 327
            ....|.||     |.|...|:.:: :...|:..::.:.|...:....||.:..:.|.:.||.::.
Zfish   269 NNTEKLDE-----MDFATELIFAQ-NHDELSVDDVRQCVLEMVIAAPDTLSISLFFMLLLLKQNS 327

  Fly   328 DEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDI 392
            ..:|::..|....:|:    ||....::..:..|:.||||:.|.:|.|.||.|.:.:|..|||..
Zfish   328 AVEEQIVQEIQSQIGS----RDVESADLQKLNVLERFIKESLRYHPVVDFIMRQSLEDDYIDGYR 388

  Fly   393 VPKGTT--LNLGLLMLGYNDRVFKDPHKFQPERFDREKPGPFEYVPFSAGPRNCIGQKFALLEIK 455
            |.|||.  ||:|.:   :....||.|::|..|.|:...|..: :.||..|||.|:|:..|::..|
Zfish   389 VAKGTNLILNIGRM---HKTEFFKKPNEFSLENFENTVPSRY-FQPFGCGPRACVGKHIAMVMTK 449

  Fly   456 TVVSKIIRNFEVLPALDELVSKDG-YIST-----TLGLQPAEK 492
            .::..::..|.|.|       :.| .|||     .|.:||.|:
Zfish   450 AILVTMLSRFTVCP-------RHGCTISTIRQTNNLSMQPVEE 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	116/471 (25%)
cyp19a1b	XP_021326198.1	CYP19A1	72..486	CDD:410709	113/456 (25%)