Protein Alignment Cyp4e1 and CYP4F11

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001122404.1
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 149/497 - (29%)
• Similarity: 256/497 - (51%)
• Gaps: 61/497 - (12%)

  Fly    46 HQMGNTPTE----ILNRFFGWWHEYGKDNFRYWIG-YYSNIMVTNPKYMEFILSSQTLISKSDV- 104
            ||...||||    .|.:....:.:    .|:.|:| .:..:::.:|..:..|.|:...::..|:
Human    63 HQGLVTPTEEGMKTLTQLVTTYPQ----GFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMI 123

  Fly   105 -YDLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNI- 167
             |....||||.|||.|.|.||.:||:|:|||||||||:.:.::.|::.....|:.:::|..|:.
Human   124 FYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSAR 188

  Fly   168 FDFQEEAHYLTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPE 232
            .|..|....:|||.:.........|..| :.|..:.|..:::..::.|.........:|::..|:
Human   189 LDMFEHISLMTLDSLQKCVFSFESNCQE-KPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPD 252

  Fly   233 YPEYSKTLKTLQDFTNEII-AKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSSK-VDGRPLTSQ 295
            ...:.:....:.|||:.:| .:|..:...|::..:| ::...|.:.|:|.||.|| .||:.|:.:
Human   253 GQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLK-NKAKSKTLDFIDVLLLSKDEDGKELSDE 316

  Fly   296 ELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRD-----ATFQEI 355
            ::..|..||||||||||.||:.:.:|.|::||:.||:...|..:::      :|     ..:.::
Human   317 DIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELL------KDREPIEIEWDDL 375

  Fly   356 STMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVI-DGDIVPKGTTLNLGLLMLGYNDRVFKDPHKF 419
            :.:..|.:.|||:.||:|.||.|.|...:|:|: ||.::|||....:.::.:.||..|:.||..:
Human   376 AQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVY 440

  Fly   420 QPERFDRE---KPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYI 481
            .|.|||:|   :..|..::||||||||||||.||:.|:|.|::..:.:|.:||...|
Human   441 DPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTE-------- 497

  Fly   482 STTLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMK 523
                                  |.....:.|::|.||.||::
Human   498 ----------------------PRRKPELILRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	139/441 (32%)
CYP4F11	NP_001122404.1	p450	52..506	CDD:365848	143/484 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154768
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.650