Protein Alignment Cyp4e1 and Cyp3a25

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 501
• Identity: 127/501 - (25%)
• Similarity: 232/501 - (46%)
• Gaps: 78/501 - (15%)

  Fly     2 WIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWW--- 63
            |::|...|.|.....||.. ||.::..:    .||..|||:|.          |.|.:.|.|
Mouse    12 WVLLVTSLVLFYIYGTYSH-GLFKKLGI----PGPKPLPLLGT----------IFNYYDGMWKFD 61

  Fly    64 ----HEYGKDNFRYWIGYYSN----IMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLL--- 117
                .:|||    .| |:|..    :.:.:|:.::.:|..:..    .|:.....:..:|.:
Mouse    62 EDCYKKYGK----IW-GFYEGPQPILAIMDPEIIKIVLVKECY----SVFTNRRFFGPVGFMKKA 117

  Fly   118 --TSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLD 180
              .|...:|.:.|.:::|.|....|::...:|.:.....:..|::..:.|.....::.....::|
Mouse   118 ITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSMD 182

  Fly   181 VICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHF-APEYP--EYSKTLKT 242
            ||..|:.||:::::.|.....||..|.|   :|.:.|.|:..:..||.| .|.|.  .:|...:.
Mouse   183 VITGTSFGVNVDSLNNPQDPFVQKAKKI---LKFKIFDPFLLSIILFPFLTPIYEMLNFSIFPRD 244

  Fly   243 LQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSS-----KVDGRPLTSQELYEEVS 302
            ..:|..:.:.:..:.|.:..:         :.::.||..::::     :...:.|:..|:..:..
Mouse   245 SMNFFKKFVKRMKKERLASNQ---------KNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAV 300

  Fly   303 TFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGR------DATFQEISTMKHL 361
            .|:|.|:|.|::.:...:|.|:.|||.|:||.:|         :.|      ..|:..:..|::|
Mouse   301 IFIFGGYDATSTSISLIMYELATHPDVQKKLQDE---------IDRTLPNKAPVTYDALMDMEYL 356

  Fly   362 DLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDR 426
            |:.:.|:.||||....:.|.::||..|:|..:||||.:.:.:..|..|...:.:|.:|.||||.:
Mouse   357 DMVVNESLRLYPIAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSK 421

  Fly   427 EKPG---PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLP 469
            |..|   |:.|:||..|||||||.:|||:.||..|..:::||.|.|
Mouse   422 ENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	118/467 (25%)
Cyp3a25	NP_062766.2	p450	39..493	CDD:278495	119/469 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810