Protein Alignment Cyp4e1 and Cyp4f1

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_062569.2
• Gene: Cyp4f1 / 56266
• RGDID: 70926
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 168/558 - (30%)
• Similarity: 273/558 - (48%)
• Gaps: 84/558 - (15%)

  Fly     2 WIVLCAFLALP-----LFLVTYFELGLL-------RRKRMLNKF-QGPSMLPLVGNAHQMGNTPT 53
            |:.|...:|.|     ||..::....:|       |..|.|..| |.|....|:|:...:  |||
  Rat     8 WLGLGPEVAFPWQTLLLFGASWILAQILTQIYAAYRNFRRLRGFPQPPKRNWLMGHVGMV--TPT 70

  Fly    54 E----ILNRFFGWWHEYGKDNFRYWIG-YYSNIMVTNPKYMEFILSSQTLISKSDV--YDLTHPW 111
            |    .|.|..|.:.:    .|..||| ....|.:.:...:..||::...::..||  |.:..||
  Rat    71 EQGLKELTRLVGTYPQ----GFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYTILKPW 131

  Fly   112 LGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKK-VADGGNIFDFQEEAH 175
            ||.|||.|.|.||.:||:|:|||||||||:.:.::.|:::.....:.|: :::|.:..|..|...
  Rat   132 LGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISEGSSRLDMFEHVS 196

  Fly   176 YLTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTL 240
            .:|||.:.........|..| :||..:.|..:::..:..|...|......|::..|:...:.|..
  Rat   197 LMTLDSLQKCVFSFDSNCQE-KSSEYIAAILELSALVAKRHQQPLLFMDLLYNLTPDGMRFHKAC 260

  Fly   241 KTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKK-----MAFLDTLLSSK-VDGRPLTSQELYE 299
            ..:.:||:.:|.:|   |::..:.|:  |||.:.|     :.|:|.||.:| .||:.|:.:::..
  Rat   261 NLVHEFTDAVIRER---RRTLPDQGL--DEFLKSKAKSKTLDFIDVLLLTKDEDGKELSDEDIRA 320

  Fly   300 EVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEI-----STMK 359
            |..||||||||||.||:.:.:|.|::||:.||:...|..:::      ||...:||     :.:.
  Rat   321 EADTFMFEGHDTTASGLSWILYNLAKHPEYQERCRQEVQELL------RDRDPEEIEWDDLAQLP 379

  Fly   360 HLDLFIKEAQRLYPSVPFIGRFTEKDYVI-DGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPER 423
            .|.:.|||:.||:|.|..|.|...:|.:: ||..:|||....:.:..:.:|..|:.||..:.|.|
  Rat   380 FLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVWPDPEVYNPFR 444

  Fly   424 FDREK---PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTL 485
            ||.|.   ..|..::||||||||||||.||:.|:|..::..:..|.:||  |:
  Rat   445 FDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLP--DD------------ 495

  Fly   486 GLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMK 523
                            .:|.....:.|::|.||.||::
  Rat   496 ----------------KEPRRQPELILRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	147/457 (32%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	147/486 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650