Protein Alignment Cyp4e1 and cyp3a65

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001032515.2
• Gene: cyp3a65 / 553969
• ZFINID: ZDB-GENE-050604-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 564
• Identity: 133/564 - (23%)
• Similarity: 235/564 - (41%)
• Gaps: 123/564 - (21%)

  Fly     2 WIVLCAFLALPLFLV-----TYF-ELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFF 60
            |.:| |||...|.:.     .|| :||:          .||..:|..|.           :.|:.
Zfish     8 WTLL-AFLVALLVIYGSWPHRYFKKLGI----------PGPKTIPFFGT-----------MLRYK 50

  Fly    61 GWWHEYGKDNF----RYWIGYYSNIMVTNPKYMEFILSSQTLIS-------------------KS 102
            ..:|.:..|.|    |.| |.|..      :.....:..||:|.                   ..
Zfish    51 DGFHVFDMDCFEKYGRIW-GIYDG------RQPVLCIMDQTIIKTVLIKECYSLFTNRRNFRLNG 108

  Fly   103 DVYDLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNI 167
            .:||        .:..:....|.:.|.:::|:|....|::...:|.::|...:|.:.|.|..|..
Zfish   109 ALYD--------AVSIAEDDDWRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAKRGES 165

  Fly   168 FDFQEEAHYLTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPE 232
            .|.:|.....::||:..||..|.|:::.|.....|...|.:   :|....:|      ||.....
Zfish   166 ADIKEFFGAYSMDVVTSTAFSVDIDSLNNPKDPFVTNIKKM---LKFDLLNP------LFLLIAF 221

  Fly   233 YPEYSKTLKTLQDF------TNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSS------ 285
            :|..:..|:.: ||      ..:.....::..||..:....|.:.::|::.||..::.|
Zfish   222 FPFMAPVLEKM-DFALFPTSVTDFFYAALQKIKSDRDTKTVAKDNTKKRVDFLQLMVDSQTGVKH 285

  Fly   286 KVDG----RPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKL-------FNEQCD 339
            |.||    :.|:..|:..:...|:|.|::|::|.:.|..|.|:.:|:..:||       |..|..
Zfish   286 KSDGEHTEKGLSDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETFPNQAP 350

  Fly   340 VMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLL 404
            |          .::.:.:|.:||..:.|:.||||....:.|..:|...|:|.::||...:.:...
Zfish   351 V----------DYETLMSMDYLDAALSESLRLYPVAARLERVCKKTVEINGLLIPKDLVVMVPTY 405

  Fly   405 MLGYNDRVFKDPHKFQPERF---DREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
            .|..:...:.:|..|:||||   ::|...|:.|:||..|||||||.:||.:.:|..:.:|::.|:
Zfish   406 ALHRDPDYWSEPESFKPERFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFD 470

  Fly   467 VLPALDEL-----VSKDGYIS----TTLGLQPAE-KKSRDAHNH 500
            | ...||.     :..:|.:|    ..|.|||.: .:|.|..|:
Zfish   471 V-SVCDETQVPLELGFNGLLSPKDPIKLKLQPRKLSQSPDVCNN 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	117/492 (24%)
cyp3a65	NP_001032515.2	cytochrome_P450	63..498	CDD:477761	108/470 (23%)