Protein Alignment Cyp4e1 and Cyp2c67

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001019890.1
• Gene: Cyp2c67 / 545288
• MGIID: 3612288
• Length: 491
• Species: Mus musculus
• Alignment Length: 526
• Identity: 120/526 - (22%)
• Similarity: 204/526 - (38%)
• Gaps: 127/526 - (24%)

  Fly     8 FLALPLFLVTYFELGLLR-RKRMLNKFQGPSMLPLVGNAH-----QMGNTPTEILNRFFGWWHEY 66
            |:.|.|.|.....|.|.| |....|...||:.||::||.|     .:|...|....       .|
Mouse     4 FVVLVLCLSFLLVLSLWRQRSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSK-------TY 61

  Fly    67 GKDNFRYWIGYYSNIMVTNPKYME--FILSSQTLISKS--DVYDLTHPWLGLGLLTSTGSKWHKH 127
            | ..|..:.|....:::...:.|:  ||...:....:.  ..:|......|:|.  |.|:.|
Mouse    62 G-PVFTLYFGSQPIVVLHGYEAMKEAFIDHGEEFSGRGRFPFFDKVTKGKGIGF--SHGNVW--- 120

  Fly   128 RKMITPAFHFNILQD-------FHEVMNENSTKFIDQLKKVADG--------------------- 164
              ..|..|..|.|::       ....:.|.:...:.:||| .:|
Mouse   121 --KATRVFTINTLRNLGMGKRTIENKVQEEAQWLMKELKK-TNGLPCDPQFIIGCAPCNVICSIV 182

  Fly   165 -GNIFDFQEEAHYLTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNK---- 224
             .|.||:::: .:|:|       :|......|..||...|.|..:...|.   :.|.:.||
Mouse   183 FQNRFDYKDK-DFLSL-------IGKVNECTEILSSPGCQIFNAVPILID---YCPGRHNKFFKN 236

  Fly   225 ------YLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLL 283
                  ||.....|:.| |..:...:||.:..:.:|.:      |.||:..|::.:.:|.|
Mouse   237 HTWIKSYLLEKIKEHEE-SLDVTNPRDFIDYFLIQRCQ------EKGIEHMEYTIEHLATL---- 290

  Fly   284 SSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGR 348
                             |:..:|.|.::.:|.:.||:.||.:|.....|:..|..:|:|..   |
Mouse   291 -----------------VTDLVFGGTESLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRH---R 335

  Fly   349 DATFQEISTMKHLDLFIKEAQR--------LYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLM 405
            ....|:.:.|.:.:..:.|.||        |...|....:|  ::|     .:||||.:...|..
Mouse   336 SPCMQDRNHMPYTNAMVHEVQRYVDLGPISLVHEVTCDTKF--RNY-----FIPKGTQVMTSLTS 393

  Fly   406 LGYNDRVFKDPHKFQPERFDREKPGPFE----YVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
            :.::...|.:|..|.|..| .:..|.|:    :||||||.|.|:|:..|.:|:...::.|::||:
Mouse   394 VLHDSTEFPNPEVFDPGHF-LDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFK 457

  Fly   467 VLPALD 472
            :.|.:|
Mouse   458 LKPLVD 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	109/494 (22%)
Cyp2c67	NP_001019890.1	p450	30..487	CDD:278495	111/500 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010