Protein Alignment Cyp4e1 and LOC4577452

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_001230597.4
• Gene: LOC4577452 / 4577452
• VectorBaseID: AGAMI1_012198
• Length: 513
• Species: Anopheles gambiae
• Alignment Length: 573
• Identity: 151/573 - (26%)
• Similarity: 254/573 - (44%)
• Gaps: 112/573 - (19%)

  Fly     3 IVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNR-----FFGW 62
            ::|..|.||.|:|  |.::          ||:....:|.|...|.:.....|...:     |...
Mosquito     4 LLLLGFGALSLYL--YCKI----------KFKFAEKIPCVEPLHPIFGNGLEFAQKNSYEIFKSL 56

  Fly    63 WHEYGKDN---FRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKW 124
            ...| |||   |:...|....|..|:|..::.|::.|..:.|..|||...  :..||||:...:|
Mosquito    57 TRAY-KDNKRIFKLCFGPIPVICPTHPDLIQKIMTEQASMDKPFVYDFMR--VDHGLLTAQYDEW 118

  Fly   125 HKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGG---NIFDFQEEAHYLTLDVICDTA 186
            ..|||.:.|.|:..||..|..:..:...|.|..::|.|...   |:.:|....   ||::||.|:
Mosquito   119 RVHRKALNPTFNTRILNSFIPIFTDCVAKMIANMEKHAGDEKPINVLEFTSPC---TLEMICRTS 180

  Fly   187 MGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPE--YSKT---------L 240
            :|..:...|.: ...::..:.|.:.:.:|.|:           |..||:  |..|         .
Mosquito   181 LGGKVLEREGK-QEFIEGLEIILHNVGLRMFN-----------ANLYPDIVYRNTRFYKAEMDAR 233

  Fly   241 KTLQDFTNEII----AKRIEVRKSGLEVG------------IKADEFS-----RKKMAFLDTLLS 284
            |....||:::|    ||..|..::.::..            :.|||..     :|...|:|.||:
Mosquito   234 KICYAFTDKVIREKRAKFEEKLRNAVDSNNNSTTADENGNVVFADEEDDMLSYKKPQIFVDQLLT 298

  Fly   285 SKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRD 349
            ...||:|.|.:|:.:.:.|.:..|::|:.:....|..||:.||:.|::...|.|:::...   .:
Mosquito   299 IPNDGKPFTHEEITDHIYTMIAAGNETSATQAAHACLLLAMHPEIQDRAAAEICELLADD---VE 360

  Fly   350 ATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFK 414
            .|.:.:..|::|:..|||:|||.|.....||.|.....:|..::|||..|.|.:..| :..:.|.
Mosquito   361 YTHETLKQMQYLERVIKESQRLCPVAAVYGRKTIGTIQLDEYVIPKGFILLLNVFAL-HRQKEFW 424

  Fly   415 DPH--KFQPERF--DREKP-GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDEL 474
            .|:  ||.|:.|  :|.|. .|:.|:|||.|||.|||.::|::.:|.::|:|::|:.:
Mosquito   425 GPNADKFDPDHFLPERVKARHPYAYLPFSGGPRGCIGSRYAMMSLKIILSQILKNYRL------- 482

  Fly   475 VSKDGYISTTLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHL-RMKQRL 526
                    ||           |....|.|.....||.|..|   || |:::|:
Mosquito   483 --------TT-----------DIPYEKMDFKFKVSMHLSFE---HLVRLERRV 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	132/494 (27%)
LOC4577452	XP_001230597.4	None