Protein Alignment Cyp4e1 and Cyp4d14

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 555
• Identity: 203/555 - (36%)
• Similarity: 301/555 - (54%)
• Gaps: 75/555 - (13%)

  Fly     1 MWIVLCAFLALPLFLVTYFELGLLRRKRMLNK------FQGPSMLPLVGNA----HQMGNTPTEI 55
            |::.|.|.|........|.      |||..||      .:||...||||||    ::...:.:.|
  Fly     1 MYLELFAILLATALAWDYM------RKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSSI 59

  Fly    56 LNRFFGWWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTST 120
            .:..|....|:||:.....:| .|..|..:.|.:|.|:|||..|.|:::|.|...|||.|||.|.
  Fly    60 FDMQFRLIAEFGKNIKTQMLG-ESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDGLLISQ 123

  Fly   121 GSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDT 185
            |.||.:.||:|||||||.||:||.||.::.|...:.:|...|||..:.:....|....:|:|.:|
  Fly   124 GKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAET 188

  Fly   186 AMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKY---LFHFAPEYP----EYSKTLKTL 243
            ||||.|||......:.||:....:..:..|..:|.:|..:   ||     ||    :.:..:|.:
  Fly   189 AMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLF-----YPKLLDKLNDAVKNM 248

  Fly   244 QDFTNEIIAKRIEVRKSGLEVGIKADEF------SRKKMAFLDTLLSSKVDGRPLTSQELYEEVS 302
            .||||.:|.:|.|:.:..:..|..||..      .:::||.||.||.|.:||.||::.::.|||.
  Fly   249 HDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTIDGAPLSNDDIREEVD 313

  Fly   303 TFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKE 367
            ||||||||||||.:.|..|||:|||:.|.::|.|..||:| .......|.:.:..:|:|:..|||
  Fly   314 TFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIG-DDKSAPVTMKLLGELKYLECVIKE 377

  Fly   368 AQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDR---VFKDPHKFQPERFDREKP 429
            :.||:||||.|||:..:|.|:||.::|..:.:   ::::.:..|   .|.||.||.|:||..|:.
  Fly   378 SLRLFPSVPIIGRYISQDTVLDGKLIPADSNV---IILIYHAQRDPDYFPDPEKFIPDRFSMERK 439

  Fly   430 G---PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAE 491
            |   ||.|.|||||||||||||||:||:|:.:||::|:||:||..:|:
  Fly   440 GEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEV----------------- 487

  Fly   492 KKSRDAHNHKYDPILSASMTLKSENGLHLRMKQRL 526
                       .|:|  ::.|:|..|::..:|.|:
  Fly   488 -----------QPVL--NVILRSTTGINCGLKPRV 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	183/457 (40%)
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	186/492 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449040
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	10	9.900