Protein Alignment Cyp4e1 and Cyp12a5

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 129/570 - (22%)
• Similarity: 234/570 - (41%)
• Gaps: 127/570 - (22%)

  Fly    23 LLRRKRMLNKFQGPSMLPLVGNAHQ---MGNTPTEILNRFFGW-----WHEYGKDNFRYWI---- 75
            :|:.:..||..|  |..|:|.:|.|   ..|.||..:.....|     :.|..|.|.....
  Fly     1 MLKGRIALNILQ--SQKPIVFSASQQRWQTNVPTAEIRNDPEWLQAKPFEEIPKANILSLFAKSA 63

  Fly    76 ---GYYSN-----------------------------IMVTNPKYMEFILSSQTL---------- 98
               |.|.|                             :|..|||..|.:..::.:
  Fly    64 LPGGKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDIL 128

  Fly    99 -----ISKSDVYDLTHPWLGL-GLLTSTGSKWHKHRKMITPAFHFNILQD-----FHEVMNENST 152
                 :.:.|.:|      |: |::.|.|..|...|.::.|.    ::|.     :.:.|::.:.
  Fly   129 RYHRTVYRKDFFD------GVQGIIPSQGKSWGDFRSIVNPV----LMQPKNVRLYFKKMSQVNQ 183

  Fly   153 KFIDQLKKVADG------GNIFDFQEEAHYLTLDVICDTAMGVSINAM--ENRSSSVVQAFKDIT 209
            :|::.:|::.|.      ||   |.|..:..||:.:...|:...:..:  ..::|...:.||.:.
  Fly   184 EFVELIKEIRDASTQEVPGN---FLETINRWTLESVSVVALDKQLGLLRESGKNSEATKLFKYLD 245

  Fly   210 YTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRK 274
            ......|....|.:.:.:...|...:..:|:.::|:.|.:.:.:.||..:...:.|:...|   .
  Fly   246 EFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRPE---H 307

  Fly   275 KMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCD 339
            :.:.|:.||  |||.:..|...:     ..:..|.|||:|.....:..|:::|::|.:|..|...
  Fly   308 EQSVLEKLL--KVDKKVATVMAM-----DMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMK 365

  Fly   340 VMGASGLGRDATFQEIS--TMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLG 402
            |:.    .:|:.|.|.|  .:.:|...|||:||:||.|....|...:|.||.|..||.||.:::.
  Fly   366 VLP----NKDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMI 426

  Fly   403 LLMLGYNDRVFKDPHKFQPERF--------------DREKPGPFEYVPFSAGPRNCIGQKFALLE 453
            .:...|::..|..|.:|.|||:              |.:...||.::||..|||.|:|::...:|
  Fly   427 PINSLYSEEYFPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEME 491

  Fly   454 IKTVVSKIIRNFEVLPALDEL--VSKDGYISTTLGLQ--PAEKKSRDAHN 499
            ::...:::||||.|     |.  .:|:.:.|..:.|.  |.:.|..|..|
  Fly   492 LELGTARLIRNFNV-----EFNHSTKNAFRSALINLPNIPLKFKFTDVPN 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	115/517 (22%)
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	107/477 (22%)