Protein Alignment Cyp4e1 and Cyp312a1

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001262008.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 156/505 - (30%)
• Similarity: 261/505 - (51%)
• Gaps: 38/505 - (7%)

  Fly     9 LALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAH----QMGNTP----TEILNRFFGWWHE 65
            |||.|:|:..|| ...|..|:.:|:..|..||.:|:.|    .:|..|    ||::|...   |:
  Fly    11 LALSLYLLYVFE-RQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATEMINEHL---HD 71

  Fly    66 YGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHKHRKM 130
            :   ..:.|:|....::..|||.::.:.|:|.|:.|::.|.:...||..||.||...||...||:
  Fly    72 H---RAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKI 133

  Fly   131 ITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSINAME 195
            :.|||::.:::.|..|..:.|...:..:.|.|:.|:..||.:.....|||.||:||:|||:.:..
  Fly   134 VMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQS 198

  Fly   196 NRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIE---- 256
            :..|..:.|.|.|...|..|..:.:.||.::|.....|....:.:|||..||..||.|||:
  Fly   199 SAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTEGIIQKRIDEINQ 263

  Fly   257 ------VRKSGLEV-GIKADEFSRKKMAFLDTLLSSK-VDGRPLTSQELYEEVSTFMFEGHDTTT 313
                  .:.|..|: |:|      :.:.||||||.|| .||:|||.:::.|||.|.:|.|.|.|.
  Fly   264 DAENRNYQSSDAELDGVK------RTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTA 322

  Fly   314 SGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFI 378
            :.:.|.:|.::.||:.|::...|...|.| .......:.:::..::.|:..|||..|:|||.|..
  Fly   323 TTLNFFMYNMTLHPEHQQRCREEVWSVCG-KDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLT 386

  Fly   379 GRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERF---DREKPGPFEYVPFSAG 440
            .|....:..|:...:|||:.:.:..:.:|.....|.||..|:|:|:   ...|.....::||.||
  Fly   387 ARKATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFMAG 451

  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVS-KDGYISTTLGLQP 489
            .|:|:||::|::.:|.|::.::|||...|..:..|. |..::.|...::|
  Fly   452 ARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVITLHTVEP 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	141/457 (31%)
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	146/480 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449061
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D214327at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	10	9.900