Protein Alignment Cyp4e1 and Cyp4d20

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 195/515 - (37%)
• Similarity: 293/515 - (56%)
• Gaps: 36/515 - (6%)

  Fly     1 MWIVLCAFLALPLFLVTYFELGLLRRKRML----NKFQGPSMLPLVGNAHQMGNTPTEILNRFFG 61
            ||:.|   :...|.|:..::.| .:|:|:|    :...||..:|::|...|..:...|   ...|
  Fly     1 MWLTL---ITGALILLLTWDFG-RKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAE---NIIG 58

  Fly    62 W----WHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGS 122
            |    :.:||| .||:||...|.|...:.:|.|.||||.||:.|..:|:...|:|..|||.|||.
  Fly    59 WVGEKFDKYGK-TFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDGLLVSTGR 122

  Fly   123 KWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAM 187
            |||..||:.|.||||.:|:.:.|:|:.:|:..:|.|:|||||....|..:......||||.:.||
  Fly   123 KWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAAM 187

  Fly   188 GVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPE--YPEYSKTLKTLQDFTNEI 250
            ||.:||..:.....::|.|.:.|....|.|...:|..:||..|..  :.:....::.:.|||:::
  Fly   188 GVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHDFTDKV 252

  Fly   251 IAKRIE-VRKS-------GLEVGIKADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFE 307
            |::|.| ||::       .|.:| .|:..|:.:||.||.||.|.::.:||:..::.|||.|||||
  Fly   253 ISERRETVRRAKADGTYRPLSLG-DAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFE 316

  Fly   308 GHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLY 372
            |.|||:|||..|:|.::|||:.|:::|.|...|:|... ....|..::..:|:||..|||..|||
  Fly   317 GDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDA-SAPVTQAQLQDLKYLDCVIKETMRLY 380

  Fly   373 PSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERF--DREK-PGPFEY 434
            |.||.|||..:|:..|....:|..|::.|.|.....:...|.||..|:||||  |:|: ...|.|
  Fly   381 PPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAY 445

  Fly   435 VPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYI-----STTLGLQP 489
            |||||||:||||||||:||:|.::||::|.:|:||..:||.....:|     ...:||:|
  Fly   446 VPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELKPMLNFILRSASGINVGLRP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	176/440 (40%)
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	174/435 (40%)