Protein Alignment Cyp4e1 and Cyp4e2

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 424/525 - (80%)
• Similarity: 464/525 - (88%)
• Gaps: 0/525 - (0%)

  Fly     1 MWIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWWHE 65
            ||.||..||||||.||.|.||...||:|:||||.||..|||:|||||||..|:|||:..|.|||:
  Fly     1 MWFVLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQ 65

  Fly    66 YGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHKHRKM 130
            ||||||.:|||.|||::||:.||:||||||||||:|||:|.||||||||||||||||||||||||
  Fly    66 YGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRKM 130

  Fly   131 ITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSINAME 195
            |||||||||||||||||||||||||..||.||.|.|||||||:||||||||||||||||||||||
  Fly   131 ITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSINAME 195

  Fly   196 NRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKS 260
            |||||:||||||:.|.|.||||.|.|||:.|:..||:||.||:||||||||||||||||||..||
  Fly   196 NRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEAHKS 260

  Fly   261 GLEVGIKADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSR 325
            |.......|||:|||||||||||||.:|||||.|:|||||||||||||||||||||.||||||||
  Fly   261 GAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSR 325

  Fly   326 HPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDG 390
            |.|||.|||.||.:|||.|.|||||||||||.||:||||||||||:|||||||||||||||||||
  Fly   326 HQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDG 390

  Fly   391 DIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKPGPFEYVPFSAGPRNCIGQKFALLEIK 455
            |:|||||||||||:|||||::||||||||:||||:.|||||||||||||||||||||||||||||
  Fly   391 DLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPGPFEYVPFSAGPRNCIGQKFALLEIK 455

  Fly   456 TVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHL 520
            |||||||||||||||||||||||||||||:||..||:|.||.:.|||||||||.:||||||||::
  Fly   456 TVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYI 520

  Fly   521 RMKQR 525
            |:|:|
  Fly   521 RLKER 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	358/434 (82%)
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	358/433 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449012
Domainoid	1	1.000	160	1.000	Domainoid score	I1269
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	1	1.000	-	-		H111093
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	12	11.800