Protein Alignment Cyp4e1 and Cyp4ac1

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 511
• Identity: 177/511 - (34%)
• Similarity: 283/511 - (55%)
• Gaps: 42/511 - (8%)

  Fly     1 MWIVLCAFLALPLFLV-----------TYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGN---- 50
            |||   |.|.:|:.|.           |||.|.|.:|.|..:.....|.:.::....:.||
  Fly     1 MWI---ALLGIPILLAVLTLLLKHINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNNLDI 62

  Fly    51 ---TPTEILNRFFGWWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWL 112
               ||..:.|.......:....|:.::..|.....|..|:..|.:..|..||:|:.||:|..|:|
  Fly    63 LNFTPASVFNFVRESTAKAKGQNYLWYFLYAPMYNVVRPEEAEEVFQSTKLITKNVVYELIRPFL 127

  Fly   113 GLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYL 177
            |.|||.||..|||..||.:|||||||:||.|..:..|...||::.|:|..|..  .:..:.....
  Fly   128 GDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAE--LELNQVIPPF 190

  Fly   178 TLDVICDTAMGVSINAME--NRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTL 240
            ||:.||:||:||.::.|.  |.....:.|.:::   :..|..:|.....:.|....:|.::.:.|
  Fly   191 TLNNICETALGVKLDDMSEGNEYRKAIHAIEEV---LIQRVCNPLMYYNWYFFVYGDYRKHLQNL 252

  Fly   241 KTLQDFTNEII-AKRIEVRKSGLEVGIKADEFSRK-KMAFLDTLLSSKVDGRPLTSQELYEEVST 303
            :.:.||::.|| .||.:.::..|.   :.|||.|| :.|.|||||:::.||: :..|.:.:||:|
  Fly   253 RIVHDFSSRIIERKRQQFQQKQLG---EVDEFGRKQRYAMLDTLLAAEADGQ-IDHQGICDEVNT 313

  Fly   304 FMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEA 368
            |||||:|||::.:.|.:.:|:.|.|.|:|.:.|..::...|.   |.:..:.:.:.:|:..|||:
  Fly   314 FMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPEDSD---DISMFQFNKLVYLECVIKES 375

  Fly   369 QRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKP---G 430
            .|::||||||||...::.|::|.::||.|.:::.:..:..:.|.|..|..|||:||..|..   .
  Fly   376 LRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNRH 440

  Fly   431 PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPA--LDELVSKDGYISTT 484
            ||.|||||||.|||||||||:||:|.:::.:||||::|||  |::|..::|.:..|
  Fly   441 PFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLEDLTFENGIVLRT 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	156/448 (35%)
Cyp4ac1	NP_608916.1	p450	86..504	CDD:278495	156/423 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460560
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	9	9.000