Protein Alignment Cyp4e1 and Cyp4d1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 542
• Identity: 204/542 - (37%)
• Similarity: 307/542 - (56%)
• Gaps: 47/542 - (8%)

  Fly     1 MWIVLCAFLALPLFL-VTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQ-MGNTPTEILNRFFGWW 63
            |::|:.|.||..||: :..:.|...|...:::...||.:|||||:.|. :|..|.|::.:.|.:.
  Fly     1 MFLVIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFM 65

  Fly    64 HEYGKDN-FRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHKH 127
            ..|.||. .:.|:|...|:::.|||.:|.:|.:.....|:..|....|||..|||.|.|.||||.
  Fly    66 ETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKR 130

  Fly   128 RKMITPAFHFNILQDFHEVMNENSTKFI-----DQLKKVADGGNIFDFQEEAHYLTLDVICDTAM 187
            ||:|||||||.||..|.||..:.|...:     |:||....|.:::|:   .:..|:|.||:|||
  Fly   131 RKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDW---INLCTMDTICETAM 192

  Fly   188 GVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIA 252
            ||||||..|..|..|||.|.|:..:..|.|:...|....:...|......|.|..|..||.:||.
  Fly   193 GVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIV 257

  Fly   253 KRIE--VRKSGLEVGIK--ADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTT 313
            :|.|  :|:...:....  ||..:::||||||.||.|.||.|||::.::.|||.||||||||||:
  Fly   258 QRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTS 322

  Fly   314 SGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFI 378
            |.:.|..|.::.||:.|:|.|.|...|:| :......:::.::.:.::||.:||..|:|||||.:
  Fly   323 SALMFFFYNIATHPEAQKKCFEEIRSVVG-NDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLL 386

  Fly   379 GRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFD----REKPGPFEYVPFSA 439
            ||...:|..|:|.::|.||.:.:..|.||..:.:|.:|:.|:|||||    .||..|:.|:||||
  Fly   387 GRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSA 451

  Fly   440 GPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDP 504
            |||||||||||:||||.:|:.::|::||     :.|....        :|              |
  Fly   452 GPRNCIGQKFAMLEIKAIVANVLRHYEV-----DFVGDSS--------EP--------------P 489

  Fly   505 ILSASMTLKSENGLHLRMKQRL 526
            :|.|.:.|:::..|..::::|:
  Fly   490 VLIAELILRTKEPLMFKVRERV 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	181/465 (39%)
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	178/461 (39%)