Protein Alignment Cyp4e1 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 165/561 - (29%)
• Similarity: 269/561 - (47%)
• Gaps: 116/561 - (20%)

  Fly     7 AFLALPLFLVTYFELGL-LRRK---RMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWWHEYG 67
            ||| |.||||.:..:.. |||:   :.|.||  ||             ||:..|     |.|:..
  Rat    22 AFL-LSLFLVLFKAVQFYLRRQWLLKALEKF--PS-------------TPSHWL-----WGHDLK 65

  Fly    68 KDNFRY---WI------------GYYSNIMVTNPKYMEFILSSQTLISKSD-----VYDLTHPWL 112
            ...|:.   |:            |..:.:::.:|.|::.:|      .:||     :|....||:
  Rat    66 DREFQQVLTWVEKFPGACLQWLSGSKTRVLLYDPDYVKVVL------GRSDPKASGIYQFLAPWI 124

  Fly   113 ----GLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGN---IFDF 170
                |.|||...|.||.:|.:|:|||||:.||:.:.::|.::.:..:|:.:|:.|..:   ||
  Rat   125 VSGTGYGLLLLNGKKWFQHWRMLTPAFHYGILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIF-- 187

  Fly   171 QEEAHYLTLDVICDTAMGVSIN-----AMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFA 230
                ||::| :..||.|..:.:     .::..|.|..:|.:|:......|..|.:..|..:::.:
  Rat   188 ----HYVSL-MTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLTFFRVRSAFYGNSIIYNMS 247

  Fly   231 PEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEF--SRKK--MAFLDTLLSSKV-DGR 290
            .:.....:..:...:.|:.:    |::||:.|:   ..:|.  :|||  :.|||.||.:|: ||:
  Rat   248 SDGRLSRRACQIAHEHTDGV----IKMRKAQLQ---NEEELQKARKKRHLDFLDILLFAKMEDGK 305

  Fly   291 PLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEI 355
            .|:.::|..||.||||||||||.||:.:..|.|:.||:.||:...|...::|.   |...|:..:
  Rat   306 SLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGD---GTSVTWDHL 367

  Fly   356 STMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVI-DGDIVPKGTTLNLGLLMLGYNDRVFKDPHKF 419
            ..:.:..:.||||.||||.||.:.|........ ||..:|||.|..:.:..|.:|...:.:|..|
  Rat   368 DQISYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYWPNPKVF 432

  Fly   420 QPERFDREKP-GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYIST 483
            .|.||..:.| ....|:|||.|.|||||::||:.|:|..|:..:..||:||....:
  Rat   433 DPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRI--------- 488

  Fly   484 TLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMKQ 524
                                |:..|.:.|||:||:|||:|:
  Rat   489 --------------------PVPMARLVLKSKNGIHLRLKK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	140/490 (29%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	141/488 (29%)