Protein Alignment Cyp4e1 and erg11

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_592990.1
• Gene: erg11 / 2542599
• PomBaseID: SPAC13A11.02C
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 475
• Identity: 101/475 - (21%)
• Similarity: 183/475 - (38%)
• Gaps: 99/475 - (20%)

  Fly    39 LPLVGNAHQMGNTPTEILNRFFGWWHE----YGKDNFRY---------WIGYYSNIMVTNPKYME 90
            :|.||:|...|..|       :.::.|    || |.|.:         ::|...|..:.|.|..:
pombe    40 IPFVGSAVAYGMDP-------YVFFRECRAKYG-DVFTFVCMGRKMTAFLGVQGNDFLFNGKLAD 96

  Fly    91 FILSSQTLIS--------KSDVYDL-THPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEV 146
              |:::...|        |..|||: .|.::             :|:|.|.....|:..:.:..:
pombe    97 --LNAEEAYSHLTTPVFGKDVVYDIPNHVFM-------------EHKKFIKSGLGFSQFRSYVPL 146

  Fly   147 MNENSTKFIDQLKKVADG-GNIFDFQEEAHYLTLDVICDTAMGVSINAMENRSSSVVQAFKDITY 210
            :......|:........| ..:.|..:....:|:.....|..|..:.      ......|.|:.:
pombe   147 ILNEMDAFLSTSPDFGPGKEGVADLLKTMPVMTIYTASRTLQGAEVR------KGFDAGFADLYH 205

  Fly   211 TIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKR----IEVRKSGLEVGIKADEF 271
            .:. :.|||   ..::|.:.| .|...:     :|..::|:.|.    |:.|:|..|
pombe   206 DLD-QGFSP---VNFVFPWLP-LPRNRR-----RDRAHKIMQKTYLKIIKDRRSSTE-------- 252

  Fly   272 SRKKMAFLDTLLSSKV-DGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFN 335
             ......:.||:|.|. |||||...|:...:...:..|..|:.:.:.:.:.||...|:..|.|:.
pombe   253 -NPGTDMIWTLMSCKYRDGRPLKEHEIAGMMIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWE 316

  Fly   336 EQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGD--IVPKGTT 398
            ||..|:|.:   .:..|.:...|..|:..|:|..||:|.:....|..::|..:.|.  ::|....
pombe   317 EQKRVVGEN---LELKFDQYKDMPLLNYVIQETLRLHPPIHSHMRKVKRDLPVPGSKIVIPANNY 378

  Fly   399 LNLGLLMLGYNDRVFKDPHKFQPERF-DR-----------------EKPGPFEYVPFSAGPRNCI 445
            |.....:....:..|.....|.|:|: ||                 .|.....|:||.||...||
pombe   379 LLAAPGLTATEEEYFTHATDFDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCI 443

  Fly   446 GQKFALLEIKTVVSKIIRNF 465
            |::||.:.:.|::||.:.::
pombe   444 GEQFAYMHLSTIISKFVHDY 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	92/442 (21%)
erg11	NP_592990.1	CYP51-like	60..492	CDD:410668	94/448 (21%)