Protein Alignment Cyp4e1 and Cyp24a1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_963966.1
• Gene: Cyp24a1 / 25279
• RGDID: 2462
• Length: 514
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 114/490 - (23%)
• Similarity: 213/490 - (43%)
• Gaps: 91/490 - (18%)

  Fly    28 RMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGW-------------WH-EYGKDNFRYWIGYY 78
            |.:....||:..||:|:          :|..|  |             :| :||: .||..:|.:
  Rat    53 RNVTSLPGPTNWPLLGS----------LLEIF--WKGGLKKQHDTLAEYHKKYGQ-IFRMKLGSF 104

  Fly    79 SNIMVTNPKYMEFILSSQTLISKSDVYDLTH-------PWL--------GLGLLTSTGSKWHK-- 126
            .::.:.:|..:|.:..:::          .|       ||.        ..||:...|.:|.:
  Rat   105 DSVHLGSPSLLEALYRTES----------AHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVR 159

  Fly   127 ---HRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVAD-GGNIFDFQEEAHYLTLDVIC---- 183
               .:|::.|.....:.:..:||:.:    |::::.::.| .|.|.|...|.:..:.:.||
  Rat   160 SAFQKKLMKPVEIMKLDKKINEVLAD----FLERMDELCDERGRIPDLYSELNKWSFESICLVLY 220

  Fly   184 DTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTN 248
            :...|:.....|..:.:.:.|.|.:..|......:|.:.:|.|  ....:..::....|:.....
  Rat   221 EKRFGLLQKETEEEALTFITAIKTMMSTFGKMMVTPVELHKRL--NTKVWQAHTLAWDTIFKSVK 283

  Fly   249 EIIAKRIEVRKSGLEVGIKADEFSRKKMA-FLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTT 312
            ..|..|::             .:|::..| ||..:....    .|:.:|||..|:.......:||
  Rat   284 PCIDNRLQ-------------RYSQQPGADFLCDIYQQD----HLSKKELYAAVTELQLAAVETT 331

  Fly   313 TSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPF 377
            .:.:.:.:|.|||:|..|.:|..|...|:..:...|   .:::..|.:|...:||:.||.|||||
  Rat   332 ANSLMWILYNLSRNPQAQRRLLQEVQSVLPDNQTPR---AEDLRNMPYLKACLKESMRLTPSVPF 393

  Fly   378 IGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERF--DREKPGPFEYVPFSAG 440
            ..|..:|..|:....:||||.|.|...:||.::..|:|.|||:|||:  ..:|..||.::||..|
  Rat   394 TTRTLDKPTVLGEYALPKGTVLTLNTQVLGSSEDNFEDSHKFRPERWLQKEKKINPFAHLPFGIG 458

  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELV 475
            .|.|||::.|.|::...:..||:.::::...:|.|
  Rat   459 KRMCIGRRLAELQLHLALCWIIQKYDIVATDNEPV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	102/436 (23%)
Cyp24a1	NP_963966.1	CYP24A1	90..508	CDD:410738	105/441 (24%)