Protein Alignment Cyp4e1 and Cyp4x1

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_663708.1
• Gene: Cyp4x1 / 246767
• RGDID: 628719
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 539
• Identity: 152/539 - (28%)
• Similarity: 258/539 - (47%)
• Gaps: 62/539 - (11%)

  Fly    10 ALPLFLVTYFELGL---------LRRKRM---LNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGW 62
            |.||.|...|.|.|         |||:|:   |..|.||:...|:|:...:.....|.|:...
  Rat    11 ARPLHLALVFCLALVLMQAVKLYLRRQRLLRDLRPFPGPTAHWLLGHQKFLQEDNMEKLDEIV-- 73

  Fly    63 WHEYGKDNFRYWIG-YYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHK 126
             .|| ...|..|:| :.:...:.:|.|.:..| |:|......::.|..|:||.|||...|.:|.:
  Rat    74 -KEY-PCAFPCWVGPFQAFFYIYDPDYAKIFL-SRTDPKTQYLHQLMTPFLGRGLLNLDGPRWFQ 135

  Fly   127 HRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKV-ADGGNIFDFQEEAHYLTLDVICDTAMGVS 190
            ||.::|||||.:||:...::|..:....:|:.:|. .......:..|..:.:|||:|...|.|..
  Rat   136 HRCLLTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQETTIEVFEHINLMTLDIIMKCAFGQE 200

  Fly   191 INAMENRS-SSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKR 254
            .|...|.: .|.|:|..::...|..|.::.|..:..:|..:|:...:.:..|.:...|.:|
  Rat   201 TNCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQCTEKI---- 261

  Fly   255 IEVRKSGLEVGIKADEFSRKKMAFLDTLLSSKV-DGRPLTSQELYEEVSTFMFEGHDTTTSGVGF 318
            |:.||..|:..:..|: ::....|||.:||::. |.:..:..:|..||:|||:.|||.:.:.:.:
  Rat   262 IQDRKKTLKDQVNQDD-TQTSQNFLDIVLSAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISW 325

  Fly   319 AVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTE 383
            .:|.|:.:|:.|::...|...::|.   |...|::::..:.:..:.|||..||.|.:|.|.|...
  Rat   326 LLYCLALNPEHQDRCRTEIRSILGD---GSSITWEQLDEIPYTTMCIKETLRLIPPIPSISRELS 387

  Fly   384 KDYVI-DGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDR---EKPGPFEYVPFSAGPRNC 444
            |...: ||..:|.|.|:.|.:..|.:|..|:|||..|.|.||.:   |:..|..::|||:|||||
  Rat   388 KPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNC 452

  Fly   445 IGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDPILSAS 509
            |||:||:||:|..::..:..|.|...|..                             .|..|:.
  Rat   453 IGQQFAMLELKVAIALTLLRFRVAADLTR-----------------------------PPAFSSH 488

  Fly   510 MTLKSENGLHLRMKQRLVC 528
            ..|:.::|::|.:|:...|
  Rat   489 TVLRPKHGIYLHLKKLPEC 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	131/442 (30%)
Cyp4x1	NP_663708.1	CYP4B-like	66..500	CDD:410771	132/475 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750