Protein Alignment Cyp4e1 and Cyp26b1

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001171184.1
• Gene: Cyp26b1 / 232174
• MGIID: 2176159
• Length: 512
• Species: Mus musculus
• Alignment Length: 527
• Identity: 123/527 - (23%)
• Similarity: 203/527 - (38%)
• Gaps: 115/527 - (21%)

  Fly    34 QGPSMLPLVGNAHQMGNTPTEILNRFFGWWHEYGKDNFRYWIGY-------YSNIMVTNPKYMEF 91
            :|....||:|..               |.|...|.       |:       |.|:..|:
Mouse    51 KGSMGFPLIGET---------------GHWLLQGS-------GFQSSRREKYGNVFKTH------ 87

  Fly    92 ILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHKH-RKMITPAFHFNILQDFHEVMNENSTKFI 155
             |..:.||..:...::....||...|.||  :|.:. |.::.|....|.:.|.|    .|..|..
Mouse    88 -LLGRPLIRVTGAENVRKILLGEHQLVST--EWPRSARVLLGPNTVANSIGDIH----RNKRKVF 145

  Fly   156 DQLKKVADGGNIFDFQEEAHYLTLD--VICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFS 218
            .:         ||..:....||...  ||.||....|   .:..:.:|.|..:.:|:.:.:|.
Mouse   146 SK---------IFSHEALESYLPKIQLVIQDTLRAWS---SQPEAINVYQEAQRLTFRMAVRV-- 196

  Fly   219 PWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMA------ 277
                   |..|:....:.....:..|.|...:.:..:::..||...||:|.:..:|.:.
Mouse   197 -------LLGFSIPEEDLGHLFEVYQQFVENVFSLPVDLPFSGYRRGIQARQILQKGLEKAIREK 254

  Fly   278 -----------FLDTLL-SSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQ 330
                       .||.|: |||..|:.:|.|||.:.....:|..:.||.|.....:..|.:||...
Mouse   255 LQCTQGKDYSDALDILIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVL 319

  Fly   331 EKLFNEQCDVMG---ASGLGRDATFQ--EISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDG 390
            ||| .|:....|   ..|...:.|.:  .:|::::||..|||..||:..|....|...:.:.:||
Mouse   320 EKL-REELRAQGLLHGGGCPCEGTLRLDTLSSLRYLDCVIKEVMRLFTPVSGGYRTVLQTFELDG 383

  Fly   391 DIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDR----EKPGPFEYVPFSAGPRNCIGQKFAL 451
            ..:|||.::...:........||||.:.|.|:||.:    :|.|.|.|:||..|.|.|:|:..|.
Mouse   384 FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAK 448

  Fly   452 LEIKTVVSKI---------IRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDP--- 504
            |.:|.:..::         .|.|..:..:..|...||......||        |::.::..|
Mouse   449 LFLKVLAVELASTSRFELATRTFPRITLVPVLHPVDGLSVKFFGL--------DSNQNEILPETE 505

  Fly   505 -ILSASM 510
             :|||::
Mouse   506 AMLSATV 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	113/480 (24%)
Cyp26b1	NP_001171184.1	CYP26B1	60..490	CDD:410730	113/486 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4824
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950