Protein Alignment Cyp4e1 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_035669.3
• Gene: Tbxas1 / 21391
• MGIID: 98497
• Length: 533
• Species: Mus musculus
• Alignment Length: 562
• Identity: 130/562 - (23%)
• Similarity: 216/562 - (38%)
• Gaps: 101/562 - (17%)

  Fly     3 IVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFF--GWWHE 65
            ||....|...|.|:.::.:....|...|. .:.|...|.|||.            .||  |:|..
Mouse    15 IVTVTLLVALLALLKWYSMSAFSRLEKLG-IRHPKPSPFVGNL------------MFFRQGFWES 66

  Fly    66 YGKDNFRY--WIGYY----SNIMVTNPKYMEFIL-SSQTLISKSDVYDLTHPWLGLGLLTSTGSK 123
            ..:...||  ..|||    .:::::.|..::.:| .:.:..|......|....:...:|.....:
Mouse    67 QLELRERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGLEPKMVADSVLLLRDRR 131

  Fly   124 WHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMG 188
            |.:.|..:..:|....|.:...::::.....:..||:.|...:.|:.|......|:||:...|.|
Mouse   132 WEEVRGALMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAFNIQRCYCCYTIDVVASVAFG 196

  Fly   189 VSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEY---------SKTLKTLQ 244
            ..:::..:.....||         ..|..|.:...:.|......:|..         :|....|.
Mouse   197 TQVDSQNSPEDPFVQ---------HCRRASTFCIPRPLLVLILSFPSIMVPLARILPNKNRDELN 252

  Fly   245 DFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSSK-------VDG------------- 289
            .|.|.:|...|.:|..      :|.|..|:.  ||..:|.::       |:|
Mouse   253 GFFNTLIRNVIALRDQ------QAAEERRRD--FLQMVLDAQHSMNSVGVEGFDMVPESLSSSEC 309

  Fly   290 --------------RPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDV 340
                          :|.|..|:..:...|:..||:..|:.:.|..|||:.|||.||:|..|....
Mouse   310 TKEPPQRCHPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLF 374

  Fly   341 MGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLM 405
            ||........:.||  .:.:||:.|.|..|:||......|...:|..:.|..:|.||.|.:.:..
Mouse   375 MGKHPAPEYHSLQE--GLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQRIPAGTVLEIAVGA 437

  Fly   406 LGYNDRVFKDPHKFQPERFDRE---KPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIR--NF 465
            |.::...:.:|..|.||||..|   :..||.|:||.||||:|:|.:..||.:|..:.:::.  .|
Mouse   438 LHHDPEHWPNPETFDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRF 502

  Fly   466 EVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDPILS 507
            |..|            .|.:.||...|.:....|..|..|:|
Mouse   503 EASP------------ETQVPLQLESKSALGPKNGVYIKIVS 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	114/495 (23%)
Tbxas1	NP_035669.3	cytochrome_P450	74..527	CDD:477761	110/483 (23%)