Protein Alignment Cyp4e1 and cyp-13A1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 125/534 - (23%)
• Similarity: 226/534 - (42%)
• Gaps: 122/534 - (22%)

  Fly     2 WIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVG---NAHQMGNTPTEILNRFFGWW 63
            |....:.:.:.:|....::....||:.::    ||...|::|   |:.. .|.|..:..|  .|.
 Worm     5 WFPWFSAIFVAVFSYYIWQWTFWRRRGVV----GPMGFPVLGVFLNSLD-NNFPFPLQCR--EWT 62

  Fly    64 HEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYD-----LTHPWLG-------LGL 116
            .::|| .:.:..|....:::::|:.:..:..:|        ||     ..:|..|       ..|
 Worm    63 KKFGK-IYGFTEGTLKTLVISDPELVHEVFVTQ--------YDNFYGRKRNPIQGDSEKEKRTNL 118

  Fly   117 LTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDV 181
            ..:.|.:|.:.|.:.:|.|..:.|:..::.:.:::.:.:..::|.:.||...|..:.....||||
 Worm   119 FAAQGFRWKRLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSAGGKQIDMLKFYQEFTLDV 183

  Fly   182 ICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKY--LFHFAPEYPEY-------- 236
            |...|||.:.:          |.||:....|..:.|    :..:  ||.....:|.:
 Worm   184 IGRIAMGQTDS----------QMFKNPIMPIVSKLF----QGNFAKLFLIGGIFPTFLVEIIRQI 234

  Fly   237 -SKTLKT-----LQDFTNEIIAKRIEVR----KSGLEVGIKADEFSRKKMAFLDTLLSSKVD--- 288
             .|.||.     :.:.|.:.|..||:.|    |:|:|:|..||        |:|..|.:|.:
 Worm   235 LLKNLKVGSFRKINEITLDAIHNRIKQREEDQKNGIEIGEPAD--------FIDLFLDAKAEDVE 291

  Fly   289 ----------------GRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKL---F 334
                            .|.||::|:..:.:.|:..|.|||...:.:|.|||:.||:.|:||   .
 Worm   292 HFGENNGDFSKSTTYTNRQLTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKKLQEEV 356

  Fly   335 NEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTE-----KDYVIDGDIVP 394
            |.:|.       ..:.|..::|.:|:::...|||.||||    :|.|..     ::..:....|.
 Worm   357 NRECP-------NPEVTIDQLSKLKYMECVFKEALRLYP----LGAFANSRRCMRNTKLGNMKVE 410

  Fly   395 KGTTLNLGLLMLGYNDRVF-KDPHKFQPERFDR-------EKPGPFEYVPFSAGPRNCIGQKFAL 451
            .||.:.:....|..:..:: .|...|:|||:..       :|.|   |:||..|||.|||.:.|.
 Worm   411 VGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQKSG---YIPFGLGPRQCIGMRLAY 472

  Fly   452 LEIKTVVSKIIRNF 465
            :|.|.::..|:|.|
 Worm   473 MEEKILLVHILRKF 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	111/465 (24%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	112/468 (24%)