Protein Alignment Cyp4e1 and cyp-13A5

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 478
• Identity: 117/478 - (24%)
• Similarity: 213/478 - (44%)
• Gaps: 70/478 - (14%)

  Fly    34 QGPSMLPLVGNAHQMGNTPTEILNRFFGWWHEYGKDNFRYWI--GYYSNIMVTNPKYMEFILSSQ 96
            :||...|..|..|:..:.....|.:...|..|||.   .|.|  |....::|:||:::..:...|
 Worm    32 KGPRGFPFFGVIHEFQDYENPGLLKLGEWTKEYGP---IYGITEGVEKTLIVSNPEFVHEVFVKQ 93

  Fly    97 TLISKSDVYD-----LTHPWLG-------LGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNE 149
                    :|     .|:|..|       ..|:::.|.:|.:.|.:.:|.|....|:.....:.|
 Worm    94 --------FDNFYGRKTNPIQGDPNKNKRAHLVSAQGHRWKRLRTLSSPTFSNKNLRKIMSTVEE 150

  Fly   150 NSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSINAMENRS--SSVVQAFKD---IT 209
            ...:.:..|...:..|...|..:.....|||:|...|||.:.:.|....  ..|...|||   :.
 Worm   151 TVVELMRHLDDASAKGKAVDLLDYYQEFTLDIIGRIAMGQTESLMFRNPMLPKVKGIFKDGRKLP 215

  Fly   210 YTIK-MRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEF-- 271
            :.:. :...:.....::...|....|.:. .:.|::...|:.:.:|....|:|:|...:..:|
 Worm   216 FLVSGIFPIAGTMFREFFMRFPSIQPAFD-IMSTVEKALNKRLEQRAADEKAGIEPSGEPQDFID 279

  Fly   272 -------------SRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLL 323
                         ....:.|..|.: :||| :.||..|:..::..|:..|:|||...:.::.|||
 Worm   280 LFLDARANVDFFEEESALGFAKTEI-AKVD-KQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLL 342

  Fly   324 SRHPDEQEKLFNE---QCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFI-GRFTEK 384
            :|||:.|:||..|   :|.       ..:.||.:||.:|:::..:|||.|:||....: .|...|
 Worm   343 ARHPEIQKKLQEEVDRECP-------NPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMK 400

  Fly   385 DYVIDGDIVPKGTTLNLGLLMLGYNDRVF-KDPHKFQPERFDR------EKPGPFEYVPFSAGPR 442
            :..:.|..:.|||.:.:....|.|:.:|: :|.::|:|||::.      .|.|   |:||..|||
 Worm   401 ETNVLGVQIEKGTNVQVDTWTLHYDPKVWGEDANEFRPERWESGDELFYAKGG---YLPFGMGPR 462

  Fly   443 NCIGQKFALLEIKTVVSKIIRNF 465
            .|||.:.|::|.|.:::.|::.:
 Worm   463 ICIGMRLAMMEKKMLLTHILKKY 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	107/444 (24%)
cyp-13A5	NP_496112.1	CYP3A-like	63..511	CDD:410678	110/447 (25%)