Protein Alignment Cyp4e1 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 502
• Identity: 139/502 - (27%)
• Similarity: 221/502 - (44%)
• Gaps: 67/502 - (13%)

  Fly     1 MWIVLCAFLALPLFLVTYF-ELGLLRRKRMLNK----FQGPSMLPLVGNAHQMGNTPTEI----L 56
            |.:::.:.|.:.:|  |:| .:.|.||:|...:    ..||.....:||..|......::    .
 Worm     1 MALLILSSLVISIF--TFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDA 63

  Fly    57 NRFFGWWHEYGKDNFRYWIGYYSNIMVTNPKYME--FILSSQTLISKS--DVYDLTHPWLGLGLL 117
            ||:|...||...:.|..:.|...||:::|.|.::  ||.:......:|  .:|:.......| |:
 Worm    64 NRWFNELHEQYGETFGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASL-LM 127

  Fly   118 TSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVI 182
            .|..|.|...|..|.|.|....::...|.:|.....|:|.|::.|..|..:|..::...||||||
 Worm   128 NSYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVI 192

  Fly   183 CDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEY----------PEYS 237
            ...|..:..|...:|:        |:.|.         ...||:.:....:          ||.|
 Worm   193 GKCAFAIDSNCQRDRN--------DVFYV---------NAKKYISNIDIRHSKIIAASVLLPELS 240

  Fly   238 KTLKTLQDFTNEIIAK--------RIEVRKSGLEVGIKADEFSRKKMAFLDTLLSSKVD-GRPLT 293
            ...|.|..:|....|:        .:..|:.|.|.....|        .|..||:.:.| .:|:|
 Worm   241 TFWKALYKYTPLADAEIPLVEGLSNVYERRRGGEGSDSVD--------LLKLLLNREDDKSKPMT 297

  Fly   294 SQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTM 358
            .||:.|....|:..|::||::.:.:..||||::|:.|:||:.|..:.....||    |:..|..|
 Worm   298 KQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKENGGL----TYDSIHNM 358

  Fly   359 KHLDLFIKEAQRLYPSV-PFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPE 422
            |:||...||..|.||.| .||.|...:|..|.|...|||..:......:..|...:..|.:|.||
 Worm   359 KYLDCVYKETLRFYPPVIHFIRRLCREDITIRGQFYPKGAIVVCLPHTVHRNPENWDSPEEFHPE 423

  Fly   423 RFD--REKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEV 467
            ||:  .||....:::||..|||.|:|.:||.:|.||.:.|::..||:
 Worm   424 RFENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFEL 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	120/426 (28%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	120/428 (28%)