Protein Alignment Cyp4e1 and cyp-43A1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_508961.3
• Gene: cyp-43A1 / 180838
• WormBaseID: WBGene00017108
• Length: 526
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 109/555 - (19%)
• Similarity: 201/555 - (36%)
• Gaps: 166/555 - (29%)

  Fly     9 LALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRF--FG-----WW--- 63
            :.||:.:.||.         .|..|:      |....|:.|..|     ||  ||     |.
 Worm     5 ILLPVAIFTYV---------FLRNFK------LYYTLHKCGLNP-----RFDIFGIKGLLWLDSS 49

  Fly    64 --HE--------YGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWL------ 112
              ||        .|...|....|....::.:|...:..|        .::.:|..|..:
 Worm    50 AAHENFTRMCSMIGDQTFSVLRGATPVVITSNVDLIHAI--------STEHFDCFHSRIPEILSD 106

  Fly   113 ------GLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFD-- 169
                  .:.:..:.|.:|.:.|.:.:.......|:.....|:...::|:|.:..::||.::..
 Worm   107 DPITSDNIHMFAAKGERWKRLRTLTSYGLSTVKLKLLFPTMDTCVSEFMDHVNSLSDGQSVVINH 171

  Fly   170 ----FQEEAHYLTLDVIC-----------DTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSP 219
                ||....|:.  ..|           :..:||...|..|.:.......:.|.|     .|..
 Worm   172 SHSLFQNHTSYVL--ARCAYGHKEKNHRVNNFLGVFSKAFGNFAELQKSTAEKIAY-----IFPE 229

  Fly   220 WK---RNKYLFHFAPEYPEYSKTLKTLQDFTNEIIA-----KRIEVRKSGL---------EVGIK 267
            .|   :|.::.||..     |.|.:...|:...:|:     |.:: ..:|:         .:|..
 Worm   230 TKLIFKNSFVGHFLK-----SATQQKFLDYLLHLISNFQSRKNVD-NNNGICCTENDHYSLLGFF 288

  Fly   268 ADEFSRKKMAFLDTLLSSKVDG----------RPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYL 322
            .:..:.||       |..|.:|          :.::.:|:..:.......|.|||::.:......
 Worm   289 FEHHNEKK-------LIEKAEGQIDMKKVKVEKSISYEEITAQCKFISVAGFDTTSNTLTLLFNF 346

  Fly   323 LSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYP----------SVPF 377
            |:.:||.|:|::..:     ........:|:.:|:::.|...|.|..||:|          :.||
 Worm   347 LANNPDVQDKIYEAE-----IKNQPEQISFETVSSLRLLQNCIFETLRLFPHASPLQTRICTEPF 406

  Fly   378 -IGR--FTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVF--KDPHKFQPERFD-----REKPGPF 432
             ||:  |.|...::   :.|.|.          ::||..  .|...|:|.||:     :.|
 Worm   407 KIGKYQFLENVQIV---VNPWGP----------HHDREIWGNDVDCFRPSRFENLTEQQRK---- 454

  Fly   433 EYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEV 467
            .::||..|||.|:|.:|||||:||...::::.:.|
 Worm   455 AFMPFGVGPRQCVGMRFALLEMKTTAFRMLQKYSV 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	91/476 (19%)
cyp-43A1	NP_508961.3	cytochrome_P450	64..514	CDD:477761	91/476 (19%)