Protein Alignment Cyp4e1 and cyp-29A2

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_505847.1
• Gene: cyp-29A2 / 179550
• WormBaseID: WBGene00011830
• Length: 503
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 184/545 - (33%)
• Similarity: 271/545 - (49%)
• Gaps: 63/545 - (11%)

  Fly     1 MWIVLCAFLALPL-FLVTYFELGLLRRKRML---NKFQGPSMLPLVGNAHQMGNTPTEILNRFFG 61
            |.|.:...:|:.| :|.|:... ||:.||..   :|..||...|:.||...:....||.|...|.
 Worm     1 MTIFIPISIAIILAYLATWIPT-LLKYKRHWQYGSKLPGPPAHPIFGNLGPIVGKKTEDLPSVFI 64

  Fly    62 WWHEYGKDNFRYWIGY-YSNIMV--------TNPKYMEFILSSQTLISKSDVYDLTHPWLGLG-L 116
            .|....:|.     |: ...:|:        .|.|....|:.|.|..:|.|.|....||||.| |
 Worm    65 NWAAEQRDQ-----GHSVMRVMILGKVYAWPLNGKAAAAIIDSTTETNKGDDYRFFDPWLGGGLL 124

  Fly   117 LTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDV 181
            |...|.:|..||||:||||||..|..:.||.|..|...||.|...:..|...|.........||:
 Worm   125 LEGYGERWKSHRKMLTPAFHFAKLGGYFEVFNNESKILIDLLSDFSASGETVDIFPYVKRCALDI 189

  Fly   182 ICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDF 246
            |.:||||:.|:|..|.....|||.:.......:.:|:|..:|:::|.......:|...|.||:..
 Worm   190 ISETAMGIKIDAQINHDHKYVQAVEGYNKIGVLVSFNPHLKNQFIFWATGYKAQYDDYLSTLKSM 254

  Fly   247 TNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDT 311
            |.::|.:|.....|| ||   ..|.|::.|.|||.:||.: :...|||:::.:||.||||.||||
 Worm   255 TEKVIKERRAAHDSG-EV---EKETSKRMMNFLDLMLSME-ESNQLTSEDIRQEVDTFMFAGHDT 314

  Fly   312 TTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVP 376
            |||...:|.:.|:.:|:.|||::.|..:|.| .....|.|.:.::.:.:||:.:||::|:...||
 Worm   315 TTSSTSWACWNLAHNPNVQEKVYKEMIEVFG-DDPNTDITLENVNNLNYLDIVLKESKRIIAPVP 378

  Fly   377 FIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERF---DREKPGPFEYVPFS 438
            .:.|....|..|||.|||.|..:.:..::|..|..|||:|.:|.|:||   :..|..|::::||.
 Worm   379 ALQRKLTNDLEIDGYIVPAGGNVTISPMVLHSNHHVFKNPTEFNPDRFLPDEVSKRHPYDFMPFL 443

  Fly   439 AGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYD 503
            ||||||||||||.|..|.::|.|:|||::.|.|                             ||:
 Worm   444 AGPRNCIGQKFAQLNEKVMISHIVRNFKIEPTL-----------------------------KYN 479

  Fly   504 ---PILSASMTLKSENGLHLRMKQR 525
               |.|  .:..|..||:.:|:.:|
 Worm   480 DTKPCL--EVVTKPSNGIPVRLIRR 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	161/467 (34%)
cyp-29A2	NP_505847.1	CYP4	75..497	CDD:410721	159/458 (35%)