Protein Alignment Cyp4e1 and cyp-25A2

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 496
• Identity: 136/496 - (27%)
• Similarity: 221/496 - (44%)
• Gaps: 60/496 - (12%)

  Fly     3 IVLCAFLALPLFLVTYF-----ELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEI----LNR 58
            ::|.:.|.|.:..:.|.     |...||.|..|.   ||.....:||..|:.:...::    .|:
 Worm     4 LILTSILILLVSFIIYILFARREQFKLREKIGLT---GPEPHWFMGNLKQIVDRKEKLGYDDSNK 65

  Fly    59 FFGWWHEYGKDNFRYWIGYYSNIMVTNPKYME--FILSSQTLISK--SDVYDLTHPWLGLGLLTS 119
            :|...|:...:.|..:.|...||:::|.:.::  ||.:......:  ..::|...  |...||.:
 Worm    66 WFNELHKQYGETFGIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPIFDSNQ--LNQSLLQN 128

  Fly   120 T-GSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVIC 183
            | .:.|...|..|.|.|....::...|.::.....|:|.|::.|..|..:|..|:...||||||.
 Worm   129 TYATGWKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDILREKASSGQKWDIYEDFQGLTLDVIG 193

  Fly   184 DTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFH---FAPEY--PEYSKTLKTL 243
            ..|..:..|...:|:        |:.| :..|.|.   .|..:.|   .|..:  ||.:...:.|
 Worm   194 KCAFAIDSNCQRDRN--------DVFY-VNARKFI---ANIDIRHSKVIAASFILPELAPLWRAL 246

  Fly   244 QDFTNEIIAK--------RIEVRKSGLEVGIKADEFSRKKMAFLDTLLSSKVD-GRPLTSQELYE 299
            ..:|....|:        .:..|:.|.|.....|        .|..||:.:.| .:|:|.||:.|
 Worm   247 YKYTPLADAEIPLVEGLSNVYERRRGGEGSDSVD--------LLKLLLNREDDKSKPMTKQEVIE 303

  Fly   300 EVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLF 364
            ....|:..|::||::.:.:..||||::|:.|:||:.|..:.....||    |:..|..||:||..
 Worm   304 NCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKENGGL----TYDSIHNMKYLDYV 364

  Fly   365 IKEAQRLYPSV-PFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFD--R 426
            .||..|.||.| .||.|....|..|.|...|||:.:......:..|...:..|.:|.||||:  .
 Worm   365 YKETLRCYPPVIHFINRRCLADITIRGQFYPKGSVVTCLPHTVHLNPENWDSPEEFHPERFENWE 429

  Fly   427 EKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEV 467
            ||....:::||..|||.|:|.:||.:|.||.:.|::..||:
 Worm   430 EKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFEL 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	127/460 (28%)
cyp-25A2	NP_497776.2	p450	38..498	CDD:278495	127/459 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4824
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760