Protein Alignment Cyp4e1 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 137/536 - (25%)
• Similarity: 249/536 - (46%)
• Gaps: 91/536 - (16%)

  Fly     2 WIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWWH-- 64
            |::|...|.| |:|......|:.::..:    .||..||.:|.          ||....|:|.
  Rat    12 WLLLVISLVL-LYLYGTHSHGIFKKLGI----PGPKPLPFLGT----------ILAYRKGFWEFD 61

  Fly    65 -----EYGKDNFRYWIGYYSN----IMVTNPKYMEFILSSQ---TLISKSDVYDLTHPWLG-LGL 116
                 :|||    .| |.|..    :.:|:|..::.:|..:   |..::.:        .| :|:
  Rat    62 KYCHKKYGK----LW-GLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRN--------FGPVGI 113

  Fly   117 L-----TSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHY 176
            |     .|...:|.:.|.:::|.|....|::...::|:.:...:..:::.::.|.....::....
  Rat   114 LKKAISISEDEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGA 178

  Fly   177 LTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHF-APEYPEYSKTL 240
            .::|||..|:.||:::::.|.....|:..|.:   :|...|.|...:..||.| .|.:...:.::
  Rat   179 YSMDVITATSFGVNVDSLNNPQDPFVEKIKKL---LKFDIFDPLFLSVTLFPFLTPLFEALNVSM 240

  Fly   241 --KTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSS-----KVDGRPLTSQELY 298
              :.:.||....:.:..|.|..         |..:::|.||..:::|     |...:.|:..|:.
  Rat   241 FPRDVIDFFKTSVERMKENRMK---------EKEKQRMDFLQLMINSQNSKVKDSHKALSDVEIV 296

  Fly   299 EEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDL 363
            .:...|:|.|::||:|.:.|.:|||:.|||.|:||   |.::..|......||:..:..|::||:
  Rat   297 AQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKKL---QDEIDAALPNKAHATYDTLLQMEYLDM 358

  Fly   364 FIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREK 428
            .:.|..||||....:.|..:.|..|:|..:||||.:.:....|..:...:.:|.:|:||||.::.
  Rat   359 VVNETLRLYPIAGRLERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKN 423

  Fly   429 P---GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELV----SKDGYISTTLG 486
            .   .|:.|:||..|||||||.:|||:.:|..:.::::||...|..:..:    ||.|.
  Rat   424 QDNINPYMYLPFGNGPRNCIGMRFALMNMKVALVRVLQNFSFQPCKETQIPLKLSKQGL------ 482

  Fly   487 LQPAEKK------SRD 496
            ||| ||.      |||
  Rat   483 LQP-EKPLLLKVVSRD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	119/463 (26%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	118/459 (26%)