Protein Alignment Cyp4e1 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 551
• Identity: 158/551 - (28%)
• Similarity: 264/551 - (47%)
• Gaps: 89/551 - (16%)

  Fly     2 WIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWWHEY 66
            ::.:.:.|.|.|.||...:. .|.|:.:|..||               ..|:...:.|||  ||.
Mouse    18 FLQVASVLGLLLLLVKAVQF-YLHRQWLLKAFQ---------------QFPSPPFHWFFG--HEK 64

  Fly    67 GK------------DNF-----RYWIGYYSNIMVTNPKYMEFILSSQTLISKSD-----VYDLTH 109
            .|            :||     |::.|..:.:.|.:|.||:.||      .:||     .|.|..
Mouse    65 FKGDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVIL------GRSDPKANGAYRLLA 123

  Fly   110 PWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEA 174
            ||:|.|||...|..|.:||:|:|||||::||:.:.:.|.::....:|:.:::||..:..:..:..
Mouse   124 PWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHI 188

  Fly   175 HYLTLDVI--CDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYS 237
            ..:|||.:  |..:...|:. ::....:.:||..|:......|..:.:.:|..::..:.......
Mouse   189 SLMTLDTVMKCAFSHKGSVQ-VDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAK 252

  Fly   238 KTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRK-KMAFLDTLLSSKVD-GRPLTSQELYEE 300
            :..:...|.|:.:    |::||..|:...:.::..:| ::.|||.||.:::: |..::.::|..|
Mouse   253 QACQLAHDHTDGV----IKLRKDQLQDEGELEKIKKKRRLDFLDILLFARMENGDSMSDKDLRAE 313

  Fly   301 VSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFI 365
            |.||||||||||.|||.:..|.|:.|||.|::...|   |....|.|...|:..:..:.:..:.|
Mouse   314 VDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREE---VQSLLGDGSSITWDHLDQIPYTTMCI 375

  Fly   366 KEAQRLYPSVPFIGRFTEKDYVI-DGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKP 429
            |||.||||.||.|.|........ ||..:|||..:.|.:..|.:|.:|:.:|..|.|.||..:.|
Mouse   376 KEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSP 440

  Fly   430 -GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKK 493
             ....::|||.|.|||||::||:.|:|.:|:..:..||:||                  .|...
Mouse   441 RHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLP------------------DPTRV- 486

  Fly   494 SRDAHNHKYDPILSASMTLKSENGLHLRMKQ 524
                      |:..|.:.|||:||::|.:|:
Mouse   487 ----------PMPLARLVLKSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	140/479 (29%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	139/475 (29%)