Protein Alignment Cyp4e1 and Cyp3a16

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 515
• Identity: 132/515 - (25%)
• Similarity: 247/515 - (47%)
• Gaps: 64/515 - (12%)

  Fly     3 IVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWW---- 63
            :||.|.:.:.|:.......||.:::.:    .||..||.:|.          :||.:.|.|
Mouse    12 LVLLAIILVLLYRYGTCTHGLFKKQGI----PGPKPLPFLGT----------VLNYYKGLWKFDM 62

  Fly    64 ---HEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGS--- 122
               .:||| .:..:.|.....::|:|:.::.:|..:..    .|:.....:..:|:::.:.|
Mouse    63 ECYEKYGK-TWGLFDGQIPLFVITDPETIKNVLVKECF----SVFTNRQDFFPVGIMSKSISLAK 122

  Fly   123 --KWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDT 185
              :|.::|.:::|.|....|::...|:.:.....:..|::.|:.|.....::.....::|||..|
Mouse   123 DEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGAYSMDVIIST 187

  Fly   186 AMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHF-APEYPEYSKTL--KTLQDFT 247
            ..||:|:::.|.....|:..|.:   ::...|.|...:..||.| .|.|...:..:  |...:|.
Mouse   188 TFGVNIDSLNNPEDPFVENAKKV---LRFDYFDPLSLSVALFPFLTPIYEMLNICMFPKDSIEFF 249

  Fly   248 NEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSS------KVDGRPLTSQELYEEVSTFMF 306
            .:.:.:..|.|         .|...:.::.|:..::.:      |...:.|:..|:..:...|:|
Mouse   250 KKFVDRMTENR---------LDSKQKHRVDFIYLMMEAYNKSKDKDSHKALSEIEITAQSIIFIF 305

  Fly   307 EGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDA--TFQEISTMKHLDLFIKEAQ 369
            .|::||:|.:.|.||.|:.|||.|:|| .|:.|    ..|...|  |:..:..|::||:.:.|..
Mouse   306 AGYETTSSILSFTVYSLATHPDIQKKL-QEEID----EALPNKAPPTYDTVMAMEYLDMVLNETL 365

  Fly   370 RLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKPG---P 431
            ||||....:.|..:||..|:|..:|||:|:.:...:|.::.:.:.:|.:||||||.:|..|   |
Mouse   366 RLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFSKENKGSIDP 430

  Fly   432 FEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAE 491
            :.|:||..|||||||.:|||:.:|..:.|:::||...|..:..:...  :|..|.|||.:
Mouse   431 YVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLK--LSRELLLQPVK 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	115/443 (26%)
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	117/446 (26%)