Protein Alignment Cyp4e1 and Cyp24a1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_034126.1
• Gene: Cyp24a1 / 13081
• MGIID: 88593
• Length: 514
• Species: Mus musculus
• Alignment Length: 490
• Identity: 116/490 - (23%)
• Similarity: 212/490 - (43%)
• Gaps: 91/490 - (18%)

  Fly    28 RMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGW-------------WH-EYGKDNFRYWIGYY 78
            |.:....||:..||:|:          :|..|  |             :| :||: .||..:|.:
Mouse    53 RNVTSLPGPTNWPLLGS----------LLEIF--WKGGLKKQHDTLAEYHKKYGQ-IFRMKLGSF 104

  Fly    79 SNIMVTNPKYMEFILSSQTLISKSDVYDLTH-------PWL--------GLGLLTSTGSKWHK-- 126
            .::.:.:|..:|.:..:::          .|       ||.        ..||:...|.:|.:
Mouse   105 DSVHLGSPSLLEALYRTES----------AHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVR 159

  Fly   127 ---HRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVAD-GGNIFDFQEEAHYLTLDVIC---- 183
               .:|::.|.....:.:..:||:.:    |:.|:.::.| .|.|.|...|.:..:.:.||
Mouse   160 SAFQKKLMKPVEIMKLDKKINEVLAD----FMGQIDELRDERGRIQDLYSELNKWSFESICLVLY 220

  Fly   184 DTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTN 248
            :...|:.....|..:.:.:.|.|.:..|......:|.:.:|.|  ....:..::....|:.....
Mouse   221 EKRFGLLQKDTEEEALTFIAAIKTMMSTFGKMMVTPVELHKRL--NTKVWQAHTLAWDTIFKSVK 283

  Fly   249 EIIAKRIEVRKSGLEVGIKADEFSRKKMA-FLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTT 312
            ..|..|:|             .:|::..| ||..:....    .|:.:|||..|:.......:||
Mouse   284 PCIDHRLE-------------RYSQQPGADFLCDIYQQD----HLSKKELYAAVTELQLAAVETT 331

  Fly   313 TSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPF 377
            .:.:.:.:|.|||:|..|::|..|...|:..:...|   .:::..|.:|...:||:.||.|||||
Mouse   332 ANSLMWILYNLSRNPQVQQRLLREIQSVLPDNQTPR---AEDVRNMPYLKACLKESMRLTPSVPF 393

  Fly   378 IGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERF-DREKP-GPFEYVPFSAG 440
            ..|..:|..|:....:||||.|.|...:||.::..|:|..||:|||: ::||. .||.::||..|
Mouse   394 TTRTLDKPTVLGEYTLPKGTVLTLNTQVLGSSEDNFEDADKFRPERWLEKEKKINPFAHLPFGVG 458

  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELV 475
            .|.|||::.|.|::...:..||:.:.::....|.|
Mouse   459 KRMCIGRRLAELQLHLALCWIIQKYNIVATDSEPV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	104/436 (24%)
Cyp24a1	NP_034126.1	CYP24A1	90..508	CDD:410738	107/441 (24%)