Protein Alignment Cyp4e1 and LOC1277758

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_061518412.1
• Gene: LOC1277758 / 1277758
• VectorBaseID: AGAMI1_003786
• Length: 989
• Species: Anopheles gambiae
• Alignment Length: 543
• Identity: 138/543 - (25%)
• Similarity: 232/543 - (42%)
• Gaps: 70/543 - (12%)

  Fly     1 MWIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLV--GNAHQMGNTPTEILNRFFGWW 63
            |::...|.:|..:|||..:......|..:      |.:.|.:  ||...:..............:
Mosquito   498 MFVYTLALVAAVIFLVLRYIYSHWERHGL------PHLKPEIPYGNIRTVAEKKESFGTAINNLY 556

  Fly    64 HEYGKDNFRYWIGYYSNIMVTNPKYMEFILSS--QTLISKSDVYDLTHPWLGLGLLTSTGSKWHK 126
            |:........::.:...|::.:|...:.|:.:  |....:....:..|......|....|.:|..
Mosquito   557 HKSSDRLLGIYLFFRPAILIRDPHLAKRIMVNDFQNFHDRGVYCNEEHDPFSANLFALPGQRWKN 621

  Fly   127 HRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSI 191
            .|..:||.|....|::....:.:...|.||::.||||...|.|.::.|....||.|.....|...
Mosquito   622 LRAKLTPTFTSGQLRNMLPTLLDVGNKLIDRMNKVADEKAIVDMRDIASRFVLDTIASVFFGFEA 686

  Fly   192 NAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQD----FTNEIIA 252
            |.:.|.....:...:...   :.|.|....|:..:| ..|...:.:: :.:||.    |..|||.
Mosquito   687 NCIHNSEDPFLSTLRRAN---RGRNFIDNFRSSGVF-ICPGLLKLTR-MTSLQPELIRFVMEIIT 746

  Fly   253 KRIEVRKSGLEVGIKADEFSRKKMAFLDTLL-----SSKVDGRPLTSQELYEEVSTFMFEGHDTT 312
            .:|:.|:.        ::.:||.  |:..|:     :.|.....|:.::....|..|...|.:|:
Mosquito   747 HQIDHREK--------NQITRKD--FVQLLIDLRREADKGSEEALSIEQCAANVFLFYIAGAETS 801

  Fly   313 TSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPF 377
            |:.:.|.::.||.:|:...||..|..::|  .....:.|::.|..||:|||.:||..|.||.:|.
Mosquito   802 TATISFTLHELSHNPEAMAKLQQEIDEMM--ERYNGEITYENIKEMKYLDLCVKETLRKYPGLPI 864

  Fly   378 IGRFTEKDY-VIDGDIV-PKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKPGPFE---YVPF 437
            :.|....|| |.|.|:| .|||.:.:.||.:..|::.|.||..:.||||| |....::   |.||
Mosquito   865 LNRECTIDYKVPDSDVVIRKGTQVIIPLLSISMNEKYFPDPELYSPERFD-ETTKNYDADAYYPF 928

  Fly   438 SAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKY 502
            .||||||||.:..:|     ||||        .|..|:||..:.:||    ||:.|
Mosquito   929 GAGPRNCIGLRQGVL-----VSKI--------GLVFLLSKFNFQATT----PAKVK--------- 967

  Fly   503 DPILSASMTLKSENGLHLRMKQR 525
              ..:|::.|..:.|..:|::.|
Mosquito   968 --FAAATVGLTPDAGFPMRIEHR 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	124/467 (27%)
LOC1277758	XP_061518412.1	None