Protein Alignment Cyp4e1 and LOC1277393

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_555875.5
• Gene: LOC1277393 / 1277393
• VectorBaseID: AGAMI1_001434
• Length: 562
• Species: Anopheles gambiae
• Alignment Length: 587
• Identity: 172/587 - (29%)
• Similarity: 280/587 - (47%)
• Gaps: 108/587 - (18%)

  Fly     2 WIVLCAFLALPLFLV--TYFELGLLRRK--RMLNKFQGPSMLPLVGNAHQ-MGNTPTEILNRFFG 61
            | ||...:|..|.||  |.|.|.:..|:  ::.|...||...||:|||:. :|.|..:|:.:...
Mosquito    20 W-VLSVTVATVLLLVAGTLFHLWMQTRRYVQLGNLIPGPVAYPLIGNANMLLGKTHNQIMEKAME 83

  Fly    62 WWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHK 126
            ..:.|| ...|.|:||:..:.:|.|..:|.||:|...:.||..|....||||.|||.|:|.||..
Mosquito    84 LSYIYG-TVARGWLGYHLVVFLTEPADVEIILNSYVHLEKSSEYRFFKPWLGDGLLISSGDKWKS 147

  Fly   127 HRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSI 191
            |||:|.||||.|:|:.|.:|.|:||...:.::.|  :.|::||..:....:|:|::.:|||| |.
Mosquito   148 HRKLIAPAFHQNVLKTFIDVFNDNSLAVVKRMSK--EVGHVFDCHDYMSEVTVDILLETAMG-ST 209

  Fly   192 NAMENRSSSVVQAFKDITYTIKM------RAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEI 250
            ...||:     :.|:.....:||      |......|...||:......|..:.|:.:...|.::
Mosquito   210 RTGENK-----EGFEYAMAVMKMCDILHKRQLKIHLRLDPLFNLTGVKKEQERLLQIIHGLTRKV 269

  Fly   251 IAKRIEV----------------------RKSG--------------------LEVGIKADEFSR 273
            :.::.::                      .|.|                    |:...:.|...:
Mosquito   270 VREKKQLYERQMAEGKMPSPSLTEIIGKKEKPGEGQLGGSPAFISQGSMLRDDLDDNDENDIGEK 334

  Fly   274 KKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQC 338
            :::||||.::.:..:|..::.:|:.|||.|.||||||||.:|..|.:.||..|...||:::.|..
Mosquito   335 RRLAFLDLMIETANNGANISDEEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQHVQEQVYAELR 399

  Fly   339 DVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGR-------FTEKDYVIDGDIVPKG 396
            .:.|.|  .|.|||.:...||:|:..|.|..|::|.||.|.|       ...|:|.|     |.|
Mosquito   400 QIFGDS--KRKATFGDTLEMKYLERVIFETLRMFPPVPMIARKINEDVQLASKNYTI-----PAG 457

  Fly   397 TTLNLGLLMLGYNDRVFKDPHKFQPERFDREKPGP---FEYVPFSAGPRNCIGQKFALLEIKTVV 458
            ||:.:|...:...:.::..|..|.|:.|..|:...   :.|:|||||||:|:|:|:|:|::|.::
Mosquito   458 TTVVIGTYKIHRREDLYPHPETFNPDNFLPERTQNRHYYSYIPFSAGPRSCVGRKYAMLKLKVLL 522

  Fly   459 SKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMK 523
            |.::|::.|:..|.|...|                            |.|.:.||..:|..::::
Mosquito   523 STVLRHYRVVSNLTEKDFK----------------------------LQADIILKRTDGFQIQLE 559

  Fly   524 QR 525
            .|
Mosquito   560 PR 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	147/509 (29%)
LOC1277393	XP_555875.5	None