Protein Alignment Cyp4e1 and LOC1273103

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_312050.1
• Gene: LOC1273103 / 1273103
• VectorBaseID: AGAMI1_012639
• Length: 509
• Species: Anopheles gambiae
• Alignment Length: 579
• Identity: 130/579 - (22%)
• Similarity: 230/579 - (39%)
• Gaps: 135/579 - (23%)

  Fly     4 VLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLP----LVGNAHQMGNT--PTEILNRFFGW 62
            ||.||    :|.|:...| .:|.|....|..|....|    |.|:|.....|  ..:|....:.:
Mosquito     7 VLAAF----IFAVSIVYL-FIRNKHNYWKDNGFPYAPNPHFLFGHAKGQAQTRHGADIHQELYRY 66

  Fly    63 WHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYD----LTH----PWLGLGLLTS 119
            :.:.|:   ||  |..|..:|.:...::..|:...|:...:|:.    .|:    |..| .|...
Mosquito    67 FKQRGE---RY--GGISQFIVPSVLVIDPELAKTILVKDFNVFHDHGVFTNAKDDPLTG-HLFAL 125

  Fly   120 TGSKWHKHRKMITPAF-------HFNILQD--------FHEVMNENSTKFIDQLKKVADGGNIFD 169
            .|..|...|:.:||.|       .|..:.|        ..:..|:...:..|.|.:
Mosquito   126 EGQPWRLMRQKLTPTFTSGRMKQMFGTIWDVGIELEKCMEQSYNQPEVEMKDILGR--------- 181

  Fly   170 FQEEAHYLTLDVICDTAMGVSINAMENRSSSV----VQAFKDITYTIKMRAFSPWKRNKYLFHFA 230
                   .|.|||...|.|:..|.::...|..    .:|| ::...|.|:.|           .|
Mosquito   182 -------FTTDVIGTCAFGIECNTLKTTDSEFRKYGNKAF-ELNTMIMMKTF-----------LA 227

  Fly   231 PEYPEYSK------TLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSSKVDG 289
            ..||...:      |...::.|..:|:.:.::.|::.          :.|:..|::.:|..|..|
Mosquito   228 SSYPTLVRNLHMKITYNDVERFFLDIVKETVDYREAN----------NVKRNDFMNLMLQIKNKG 282

  Fly   290 R--------------PLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDV 340
            :              .:|..||..:...|...|.:|:::...|.:|.|:::||.||:|..|....
Mosquito   283 KLDDSDDGSLGKGEVGMTQNELAAQAFVFFLAGFETSSTTQSFCLYELAKNPDIQERLREEINRA 347

  Fly   341 MGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDG--DIVPKGTTLNLGL 403
            :..:  |.:.|:..:..:|:||..|.|..|.||.|..:.|....||:|.|  .::||.|.:.:..
Mosquito   348 IAEN--GGEVTYDVVMNIKYLDNVIDETLRKYPPVESLTRVPSVDYLIPGTKHVIPKRTLVQIPA 410

  Fly   404 LMLGYNDRVFKDPHKFQPERF---DREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNF 465
            ..:..:...:.||.:|.|:||   :.:|..||.::||..|||.|||.:|.|::.|..:..::|.|
Mosquito   411 YAIQRDPDHYPDPERFNPDRFLPEEVKKRHPFTFIPFGEGPRICIGLRFGLMQTKVGLITLLRKF 475

  Fly   466 EVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMKQ 524
            ...|:                       :|.....:|||.:   :|:..:.|.:|::::
Mosquito   476 RFSPS-----------------------ARTPERVEYDPKM---ITIAPKAGNYLKVEK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	111/503 (22%)
LOC1273103	XP_312050.1	CYP6-like	70..501	CDD:410679	111/502 (22%)