Protein Alignment Cyp4e1 and LOC1272070

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_310940.6
• Gene: LOC1272070 / 1272070
• VectorBaseID: AGAMI1_004112
• Length: 552
• Species: Anopheles gambiae
• Alignment Length: 571
• Identity: 198/571 - (34%)
• Similarity: 291/571 - (50%)
• Gaps: 85/571 - (14%)

  Fly     4 VLCAFLALPLFLVTYFELGLL---RRK----RMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFG 61
            |...|..:.|.|:|.....:.   ||:    |.::|..||:.||::||...:.....||.||...
Mosquito    17 VFTLFSPVTLLLLTTVSCAIYVYNRRRAHIVRHIDKIPGPAGLPILGNTLHINVDHDEIFNRIIA 81

  Fly    62 WWHEYGK-DNF-RYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKW 124
            ....||: ..| |.|.|....:|::....:|.||.||..|.||..|:...||||.|||||.|.||
Mosquito    82 IRKLYGRIQGFSRAWNGPLPYVMISKASAVERILGSQKHIEKSHDYEFLKPWLGTGLLTSAGKKW 146

  Fly   125 HKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAH----YLT---LDVI 182
            |..||::||||||.||.||.::..|.|...:.:|:  |:.||     |:..    |:|   |||:
Mosquito   147 HPRRKILTPAFHFKILDDFVDIFQEQSAVLVKRLE--AELGN-----EQGFNCFPYVTLCALDVV 204

  Fly   183 CDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFT 247
            |:||||..:||..|..|..|:|...|...::.|....|.:..::|....:|..:.|.|..|.:|:
Mosquito   205 CETAMGRQVNAQCNSDSDYVKAVYQIGSIVQNRQQKIWLQPDFIFKLTQDYKNHQKCLAILHEFS 269

  Fly   248 NEIIAKR-IEVRKSGLEVG----------------------------IKADEFSRKK-MAFLDTL 282
            |.:|.:| .|:|:...::|                            :..:|..||| :||||.|
Mosquito   270 NRVIHERKEEIRRQKQQLGDKNNNNNNNGGGGAAGTDQDGNNNKDDYLSHEELGRKKRLAFLDLL 334

  Fly   283 LSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLG 347
            :.:..||..|:.:::.|||.||||||||||::.:.:.:.||...|..|:::..|...:||.. ..
Mosquito   335 IEASQDGAVLSHEDIREEVDTFMFEGHDTTSAAISWILLLLGTEPTIQDRIVEEIDQIMGGD-RE 398

  Fly   348 RDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRV 412
            |..|.||::.||:|:..|||..|||||||.|.|...:|..|||.::|.|||..:.:..|..|..|
Mosquito   399 RFPTMQELNEMKYLEACIKEGLRLYPSVPLIARRLTEDVDIDGYVLPAGTTAMIVVYQLHRNPEV 463

  Fly   413 FKDPHKFQPERFDREK---PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDEL 474
            |.:|.||.|:.|..|.   ..|:.|:|||||||||||||||:||.|:::|.::|.:.|
Mosquito   464 FPNPDKFNPDHFLPENCRGRHPYAYIPFSAGPRNCIGQKFAVLEEKSIISAVLRRYRV------- 521

  Fly   475 VSKDGYISTTLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMKQR 525
                                 :|.:.:.:..|...:.|:.:|||.:|:.:|
Mosquito   522 ---------------------EAVDRRENLTLLGELILRPKNGLRIRIARR 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	175/493 (35%)
LOC1272070	XP_310940.6	None