Protein Alignment Cyp4e1 and LOC1269419

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_308056.6
• Gene: LOC1269419 / 1269419
• VectorBaseID: AGAMI1_000410
• Length: 510
• Species: Anopheles gambiae
• Alignment Length: 548
• Identity: 129/548 - (23%)
• Similarity: 236/548 - (43%)
• Gaps: 70/548 - (12%)

  Fly     3 IVLCAFLALPLFLVTYFELGLLRRKR---MLNKFQGPSMLPLVGN-AHQMGNTPTEILNRFFGWW 63
            :::..|:.  :|.:.|:......|||   :..:..||...||:|: ...:|.:|.|::.......
Mosquito     8 MIVLVFIG--VFALVYYVNFRRTRKRLYELAERIPGPFDYPLIGSMLLTIGKSPLELVTHLMELM 70

  Fly    64 HEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHKHR 128
            |.. ....|.|:|.:..::|..|:.::.:|||...:.|..:||...  |..||..:...:|.:||
Mosquito    71 HHL-PSPMRAWLGPFLLVVVDRPEMVQDVLSSPDCVQKPFMYDFFR--LSKGLFGAPADQWKRHR 132

  Fly   129 KMITPAFHFNILQDFHEVMNENSTKFIDQLK-KVADGGNIFDFQEEAHYLTLDVICDTAMGVSIN 192
            |::..:|....|:.|...:|..:.:|..:|. ||:  |..||........||..|..|.:|..::
Mosquito   133 KLLNASFSPAALKSFVPTLNAKADQFTRELAGKVS--GECFDVHRLLARYTLVTISSTTLGADLS 195

  Fly   193 -----AMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIA 252
                 .:|..:|:.:|.|.:..    .|.:..|.....::.....:.|.....|:.:..:.:||.
Mosquito   196 VEKREVLEEYTSNAIQMFTNCF----ERIYKAWLHPDCVYRMTAAFREEEIRFKSFKQMSRKIIT 256

  Fly   253 KR----IEVRKSGLEVGIKAD-----EFSRKKMAFLDTLLSSKVD-GRPLTSQELYEEVSTFMFE 307
            .|    .|.:.:..|....:|     |..:.|: |::.|.....| ...:......:.:.|.||.
Mosquito   257 MRQALLSETKPTKAEYQQDSDPEENQELPKAKI-FIERLEEIAHDPANGIDEDGFQQHIDTMMFG 320

  Fly   308 GHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLY 372
            |:||:...:...:..|..:||.|||::.|..||:...    ..::::::.:..|::|:||..||.
Mosquito   321 GNDTSAQALSNTLLTLGMYPDWQEKVYQEIMDVVPHG----PVSYEDLTKLTLLEMFLKETMRLL 381

  Fly   373 PSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVF--KDPHKFQPERFDREKPG---PF 432
            |....|.|...|:.......:|.|..:.:..|.: :.|:..  .|...|.|:.|..|:..   |:
Mosquito   382 PITGLIARTPMKEVQAQDVTLPVGCFVLIPFLKM-HRDKTIWGPDAETFNPDNFLPERCAQRHPY 445

  Fly   433 EYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDA 497
            .::|||.|||||||.|:..|.:|.::..::|.:.              |||.:.|:
Mosquito   446 AFIPFSQGPRNCIGMKYGWLSMKILLCHVVRQYR--------------ISTDIKLR--------- 487

  Fly   498 HNHKYDPILSASMTLKSENGLHLRMKQR 525
                 |..||.|:.:|......:|::||
Mosquito   488 -----DIKLSLSLVMKLNTKHLIRLEQR 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	111/472 (24%)
LOC1269419	XP_308056.6	None