Protein Alignment Cyp4e1 and Cyp27b1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_446215.1
• Gene: Cyp27b1 / 114700
• RGDID: 69192
• Length: 501
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 125/558 - (22%)
• Similarity: 212/558 - (37%)
• Gaps: 144/558 - (25%)

  Fly    28 RMLNKFQGPSMLPLVGNAHQMGNTPTEILNRF----FGWWHE--------YGKDNFRYWIGYYS- 79
            |.|:...|||             ||:.:...|    ....||        ||.    .|.|.:.
  Rat    28 RSLSDIPGPS-------------TPSFLAELFCKGGLSRLHELQVHGAARYGP----IWSGSFGT 75

  Fly    80 --NIMVTNPKYMEFILSSQTLISKSDVYDLTHPW--------LGLGLLTSTGSKWHKHRKMITPA 134
              .:.|.:|..:|.:|..::...:...:.   .|        ...||||:.|.:|.:.|.::.|.
  Rat    76 LRTVYVADPALVEQLLRQESHCPERCSFS---SWSEHRRRHQRACGLLTADGEEWQRLRSLLAPL 137

  Fly   135 FHFNILQ-----DFHEVMNENSTKFIDQLKKVADGGN-----IFDFQEEAHYLTLDVICDTAMGV 189
                :|:     .:...::...:..:.:|::....|:     :.|...|.:...|:.|....:|.
  Rat   138 ----LLRPQAAAGYAGTLDSVVSDLVRRLRRQRGRGSGLPDLVLDVAGEFYKFGLEGIGAVLLGS 198

  Fly   190 SINAMENR----SSSVVQA----FKDITYTIKMRAF------SPWKRN----KYLFHFAPEYPEY 236
            .:..:|..    :.:.::|    |.....|:.|.::      .||.|.    ..:|.||.::.|.
  Rat   199 RLGCLEAEVPPDTETFIEAVGSVFVSTLLTMAMPSWLHRLIPGPWARLCRDWDQMFAFAQKHVEQ 263

  Fly   237 SKTLKTLQDFTNEIIAKRIEVRKSG-----LEVGIKADEFSRKKMAFLDTLLSSKVDGRPLTSQE 296
            .:              ....||..|     |..|.....|          |...||     :.|.
  Rat   264 RE--------------GEAAVRNQGKPEEDLPTGHHLTHF----------LFREKV-----SVQS 299

  Fly   297 LYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQ--EISTMK 359
            :...|:..:..|.||.::.:.:|:|.|||||:.|..|.:|   :.||...|..|..|  .:|.:.
  Rat   300 IVGNVTELLLAGVDTVSNTLSWALYELSRHPEVQSALHSE---ITGAVNPGSYAHLQATALSQLP 361

  Fly   360 HLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERF 424
            .|...|||..||||.||...|..::|..:...::|:.|.::|.......:...|::|:.|.|.|:
  Rat   362 LLKAVIKEVLRLYPVVPGNSRVPDRDICVGNYVIPQDTLVSLCHYATSRDPAQFREPNSFNPARW 426

  Fly   425 DREKPG--PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGL 487
            ..|.|.  ||..:||..|.|:|||::.|.||::..:::|:.:|||||              ..|.
  Rat   427 LGEGPAPHPFASLPFGFGKRSCIGRRLAELELQMALAQILTHFEVLP--------------EPGA 477

  Fly   488 QPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMKQR 525
            .|.:..:|              ..|..|..:||:...|
  Rat   478 LPVKPMTR--------------TVLVPERSIHLQFVDR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	110/499 (22%)
Cyp27b1	NP_446215.1	CYP27B1	61..496	CDD:410741	112/505 (22%)