Protein Alignment Cyp4e1 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 530
• Identity: 143/530 - (26%)
• Similarity: 244/530 - (46%)
• Gaps: 75/530 - (14%)

  Fly     1 MW---IVLC------AFLALPLFLVTYFELGLLRRKRMLNKFQ---GPSMLPLVGNAHQMGNTPT 53
            ||   ||.|      .||.:.:..|..|.......|.|..|:.   ||..     ::..:|:.||
 Frog     1 MWHSVIVHCLSWVYSGFLLIIIGAVVAFLAYCAYIKYMHLKYDDIPGPPR-----DSFLLGHIPT 60

  Fly    54 --------EILNRFFGWWHE-YG---KDNFRYWIGYYSNIMVTNPKYM-EFILSSQTLISKSDVY 105
                    .:::..|..|.| ||   |.|..:.:..||    |:|:.: |.::||:   ...|.|
 Frog    61 LSKAEENYSVVHDLFLHWAEIYGPVFKINILHRVMIYS----TSPESVKECLMSSK---YPKDPY 118

  Fly   106 DLTH-------PWLGLGLLTSTG-SKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVA 162
            ....       .:||.||||... ..|:..|:::.|||....|::...:.||.:.:.:::|::.|
 Frog   119 TYNQLFNLFGKRFLGKGLLTDPDHDHWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEKA 183

  Fly   163 DGGNIFDFQEEAHYLTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLF 227
            ||..........:.:|||||...|.|:.:..:|...:....|...: .|..||    :.:|.|:.
 Frog   184 DGHQEVSMHSIINRVTLDVITKVAFGMDLGLVEGNKTDFPNAISKV-LTGMMR----YMQNPYMQ 243

  Fly   228 HFAPEYP---EYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSR-KKMAFLDTLLSSKVD 288
            :|...:.   |..::...|:....|.|::|.:..::|.|  :..|..:: .:.|.|:..|..::
 Frog   244 YFPKHWAFVREVQESADLLRKTGKECISQRKKAMQNGEE--LPKDILTKILQCAELENALDDEI- 305

  Fly   289 GRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQ 353
                    :.:...||...|.:||.:.:.|.|..|:|.|:...||..|..:|:   |..||.::.
 Frog   306 --------MLDNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVI---GFKRDISYD 359

  Fly   354 EISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHK 418
            :|..:.::...:||:.|.||..|...|:.::|.:.:|..:|.|.::.....::|..::.|:||.|
 Frog   360 DIQNLNYMTQVLKESLRFYPPGPGTSRYLKEDTIFEGIKIPGGVSITFNTYVMGRMEKFFQDPCK 424

  Fly   419 FQPERFDREKPGP-FEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGY-I 481
            |.||||......| |.|.||:.|||:|:||.|:.||.|.::||:|:.||.     |||....: |
 Frog   425 FDPERFHPAAVKPYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEF-----ELVPGQSFGI 484

  Fly   482 STTLGLQPAE 491
            ..|..|:|.:
 Frog   485 KDTGTLRPRD 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	121/439 (28%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	126/454 (28%)