Protein Alignment Cyp4e1 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_031761583.1
• Gene: cyp26c1 / 100489980
• XenbaseID: XB-GENE-1219115
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 596
• Identity: 122/596 - (20%)
• Similarity: 202/596 - (33%)
• Gaps: 192/596 - (32%)

  Fly     5 LCAFLALPLFLVTYFELGLLR----RKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFG---- 61
            |.:.|:|.|.|....:|..||    |.|       .|.|||...:  || .|      |||
 Frog    16 LTSALSLVLLLAASHQLWSLRWHSTRDR-------GSSLPLPKGS--MG-WP------FFGETLH 64

  Fly    62 W------WHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTST 120
            |      :|...::.       |.||..|:       |..:.:|..:...::....||...|.||
 Frog    65 WLVQGSSFHSSRREK-------YGNIFKTH-------LLGKPVIRVTGAENIRKILLGEHHLVST 115

  Fly   121 GSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDT 185
              :|.:..::|..:   |.|.:....::....|   .:.||.....:..:....|......:...
 Frog   116 --QWPQSTQIILGS---NTLSNSIGELHRQKRK---MMSKVLSSAALESYLPRIHEAVRWEVRSW 172

  Fly   186 AMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEI 250
            ..||.       ..|::...|.:|:.|..|         .|...:....::.:..:|.:.....:
 Frog   173 CRGVG-------PVSMLSCAKALTFRIAAR---------ILLGLSLTDTQFQELTRTFEQLVENL 221

  Fly   251 IAKRIEVRKSGLEVGIKA--------DEFSRKKMA---------FLDTLL-SSKVDGRPLTSQEL 297
            ....:::..|||..|:||        :|..::|::         .||.|: |:|..|:.:..|||
 Frog   222 FCLPLDIPFSGLRKGMKARDTLHQYMEEAIKEKLSKRDPDACEDALDYLINSAKEGGKEINMQEL 286

  Fly   298 YEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKL--------FNEQCD--------------- 339
            .|.....:|....||.|.....|.||.:||....|:        .:|.|:
 Frog   287 KESAIELIFAAFLTTASASTSLVLLLLKHPSAIHKIRQELASHGLSEHCEQCLPATENPNNNILQ 351

  Fly   340 ---------------VMGASG-----------LGRDATFQE------------------------ 354
                           |||..|           |..|.|.|:
 Frog   352 DNGHQCLTAGCQLPLVMGTEGQVKTLWEQTKQLLTDRTDQDPQNSLSSKNLVNGENRIQEAPCSH 416

  Fly   355 -----------------------------ISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDG 390
                                         :.::.:||..:||..||.|.|....|...:.:.:||
 Frog   417 DKSNCSPVPGKLQNSVFEGTCQQNISLEKLKSLHYLDCVVKEVLRLLPPVSGGYRTALQTFELDG 481

  Fly   391 DIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERF----DREKPGPFEYVPFSAGPRNCIGQKFAL 451
            ..:|||.::...:........|:::...|.||||    |..|.|.|.|:||..|.|:|||::.|.
 Frog   482 YQIPKGWSVMYSIRDTHETAAVYQNAEMFDPERFSTERDEGKLGRFNYIPFGGGARSCIGKELAQ 546

  Fly   452 LEIKTVVSKII 462
            :.:|.:..:::
 Frog   547 IILKILAMELV 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	100/519 (19%)
cyp26c1	XP_031761583.1	cytochrome_P450	59..588	CDD:477761	104/537 (19%)