Protein Alignment Cyp4e1 and Cyp2c69

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001097995.1
• Gene: Cyp2c69 / 100043108
• MGIID: 3721049
• Length: 491
• Species: Mus musculus
• Alignment Length: 546
• Identity: 126/546 - (23%)
• Similarity: 206/546 - (37%)
• Gaps: 148/546 - (27%)

  Fly     8 FLALPLFLVTYFELGLLR-RKRMLNKFQGPSMLPLVGNAH------------QMGNTPTEILNRF 59
            |:.|.|.|.....|.|.| |....|...||:.||::||.|            ....|...:...:
Mouse     4 FVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLY 68

  Fly    60 FGWWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYD--LTHPWL-----GLGLL 117
            ||                 |..:|....| |.|  .:.||...:|:.  .:.|:.     |.|:.
Mouse    69 FG-----------------SQPIVVLHGY-EAI--KEALIDHGEVFSGRGSFPFFDKVSKGKGIG 113

  Fly   118 TSTGSKWHKHRKMITPAFHFNILQD-------FHEVMNENSTKFIDQLKKVADGG---------- 165
            .|.|:.|     ..|..|..|.|::       ....:.|.:...:.:||| .:|.
Mouse   114 FSHGNVW-----KATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKK-TNGSPCDPQFIIGC 172

  Fly   166 ------------NIFDFQEEAHYLTLDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFS 218
                        |.||:::: .:|:|       :|......|..||...|.|..:...|.   :.
Mouse   173 APCNVICSIVFQNRFDYKDK-DFLSL-------IGKVNECTEILSSPGCQIFNAVPILID---YC 226

  Fly   219 PWKRNK----------YLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSR 273
            |.:.||          ||.....|:.| |..:...:||.:..:.:|.:      :.||:..|::.
Mouse   227 PGRHNKFFKNHTWIKSYLLEKIKEHEE-SLDVTNPRDFIDYFLIQRRQ------DKGIEHMEYTI 284

  Fly   274 KKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQC 338
            :.:|.|                     |:..:|.|.:|.:|.:.||:.||.:|.....|:..|..
Mouse   285 EHLATL---------------------VTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEID 328

  Fly   339 DVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGD------IVPKGT 397
            :|:|..   |....|:...|.:.:..:.|.||.....|     |...:.:..|      .:||||
Mouse   329 NVIGRH---RSPCMQDRKHMPYTNAMVHEVQRYVDLGP-----TSLVHEVTCDTKFRNYFIPKGT 385

  Fly   398 TLNLGLLMLGYNDRVFKDPHKFQPERFDREKPGPFE----YVPFSAGPRNCIGQKFALLEIKTVV 458
            .:...|..:.::...|.:|..|.|..| .:..|.|:    :||||||.|.|:|:..|.:|:...:
Mouse   386 QVMTSLSSVLHDSTEFPNPEVFDPGHF-LDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFL 449

  Fly   459 SKIIRNFEVLPALDELVSKDGYISTT 484
            :.|::||::.|.:|   .||  |.||
Mouse   450 TTILQNFKLKPLVD---PKD--IDTT 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	110/502 (22%)
Cyp2c69	NP_001097995.1	p450	30..487	CDD:278495	117/520 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010