Protein Alignment Cyp4e1 and Cyp3a59

DIOPT Version :9

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001098630.1
• Gene: Cyp3a59 / 100041449
• MGIID: 3769707
• Length: 503
• Species: Mus musculus
• Alignment Length: 500
• Identity: 125/500 - (25%)
• Similarity: 235/500 - (47%)
• Gaps: 76/500 - (15%)

  Fly     2 WIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWW--- 63
            |::|...|.......||.. ||.::..:    .||..|||.|.          |.|.|.|.|
Mouse    12 WVLLVTSLVFFYIYGTYSH-GLFKKLGI----PGPKPLPLFGT----------IFNYFDGMWKFD 61

  Fly    64 ----HEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDL--THPWLG-LGLL---- 117
                .:||| .:.:::|....:.:.:|:.::.:|       ..:.|.:  ..|.|| :|.|
Mouse    62 EDCYKKYGK-IWGFYVGPKPILAIMDPEIIKIVL-------VKECYSVFTNRPTLGPVGFLKKSI 118

  Fly   118 -TSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDV 181
             .|...:|.:.|.:::|.|....|::...:|.:.....:..|::..:.|...:.::.....::||
Mouse   119 TISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINMKDIFGAYSMDV 183

  Fly   182 ICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHF-APEYPEYSKTL--KTL 243
            |..|:.||:|:::.|..:..||..|.|   :|.:.|.|:..:..||.| .|.|...:.::  :..
Mouse   184 ITGTSFGVNIDSLNNPQNPFVQKTKKI---LKFKIFDPFLLSTILFPFLTPIYEMLNLSIFPRDS 245

  Fly   244 QDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSS-----KVDGRPLTSQELYEEVST 303
            .:|..:.:.:..:.|.:..:         :.::.||..::::     :...:.|:..|:..:...
Mouse   246 MNFFKKFVKRMKKERLASKQ---------KNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVI 301

  Fly   304 FMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGR------DATFQEISTMKHLD 362
            |:|.|:|.|::.:...:|.|:.|||.|:||.:|         :.|      ..|:..:..|::||
Mouse   302 FIFGGYDATSTSISLIMYELATHPDVQKKLQDE---------IDRTLPNKAPVTYDALMDMEYLD 357

  Fly   363 LFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDRE 427
            :.:.|:.||||:...:.|.::||..|:|..:||||.:.:.:..|..|...:.:|.:|.|.||.:|
Mouse   358 MVVNESLRLYPTAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPGRFSKE 422

  Fly   428 KPG---PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLP 469
            ..|   |:.|:||..|||||:..:|||:.:|..|..:::||.|.|
Mouse   423 NEGNIDPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	117/466 (25%)
Cyp3a59	NP_001098630.1	p450	39..493	CDD:278495	117/467 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810